Biochemistry/ Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto, JR., Lubert Stryer

Table of contents

Part I: The Modular Design of Life

1. Biochemistry: An Evolving Science 1

2. Protein Composition and Structure 27

3. Exploring Proteins and Proteomes 65

4. DNA, RNA and the flow of Genetic Information 105

5. Exploring Genes and Genomes 135

6. Exploring Evolution and Bioinformatics69

7. Hemoglobin: Portrait of a protein in Action 191

8. Enzymes: Basic concepts and Kinetics 215

9. Catalytic Strategies 251

10. Regulatory strategies 285

11. Carbohydrates 315

12. Lipids and Cell Membranes 341

13. Membrane Channels and Pumps 367

14. Signal-Transduction Pathways 397

Part II: Transducing and Storing Energy

15. Metabolism: Basic Concepts and Design 423

16. Glycolysis and Gluconeogesis 449

17. The Citric Acid Cycle 495

18. Oxidative Phosphorylation 523

19. The Light Reactions of Photosynthesis 565

20. The calvin Cycle and the pentose phosphate pathway 589

21. Glycogen Metabolism 617

22. Fatty Acid Metabolism 643

23. Proten Turnover and Amino Acid Catabolism 681

Part III: Synthesizing the Molecules of Life

24. The Biosynthesis of Amino Acids 713

25. Nucleotide Biosynthesis 743

26. The Biosynthesis of Membrane Lipids and Steroids 767

27. The Integration of mMetabolism 801

28. DNA Replication, Repair, and Recombination 827

29. RNA synthesis and Processing 859

30. Protein Synthesis 893

31. The Control of Gene Expression in Prokaryotes 925

32. The Control of Gene Expression in Eukaryotes 941

Part IV : Responding to Environmental Changes

33. Sensory Systems 961

34. The Immune System 981

35. Molecular Motors 1011

36. Drug Development 1033

Index.