Quality of life assessment in clinical trials : methods and practice / edited by Maurice J. Staquet, Ron D. Hays, and Peter M. Fayers.
Series: Oxford medical publicationsPublication details: Oxford ; New York : Oxford University Press, c1998.Description: x, 360 p. ; 25 cmISBN:- 0192627856
- 9780192627858
- W 20.55.C5 Q15 1998
Item type | Current library | Call number | Copy number | Status | Date due | Barcode |
---|---|---|---|---|---|---|
Book Open Access | Health Sciences Library | W 20.55.C5 Q15 1998 (Browse shelf(Opens below)) | 1 | Available | MBAL22031810 |
Includes bibliographical references and index.
Contents
Part I: Introduction
1. Understanding and using health-related quality of life instruments within clinical research studies
Part II: Primary issues specific to quality of life trials
2. Guidelines for measuring health-related quality of life in clinical trials
3. Sample sizes for randomized trials measuring quality of life
4. Cross-cultural issues in the use of quality of life measures in randomized controlled trials
5. Profile versus utility based measures of outcome for clinical trials
Part III: Decision theory and preference assessment
6. Introduction to decision theory and utilities
7. Using decision theory in clinical research: applications of quality-adjusted life-years
8. Possibilities for summarizing health-related quality of life when using a profile instrument
Part IV: Psychometry
9. Questionnaire scaling: models and issues
10. Assessing reliability and validity of measurement in clinical trials
11. Item response theory models
12. Factor analysis
Part V: Data analysis
13. Methods of analysis for longitudinal studies of health-related quality of life
14. Analysis of incomplete quality of life data in clinical trials
15. Using the Q-TWiST method for treatment comparisons in clinical trials
Part VI: Interpreting and reporting results of QoL clinical trials
16. Clinical interpretation of health-related quality of life data
17. Summarizing quality of life data using graphical methods
18. Guidelines for reporting results of quality of life assessments in clinical trials
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