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Quality of life assessment in clinical trials : methods and practice / edited by Maurice J. Staquet, Ron D. Hays, and Peter M. Fayers.

Contributor(s): Series: Oxford medical publicationsPublication details: Oxford ; New York : Oxford University Press, c1998.Description: x, 360 p. ; 25 cmISBN:
  • 0192627856
  • 9780192627858
Subject(s): NLM classification:
  • W 20.55.C5 Q15 1998
Online resources:
Contents:
Contents Part I: Introduction 1. Understanding and using health-related quality of life instruments within clinical research studies Part II: Primary issues specific to quality of life trials 2. Guidelines for measuring health-related quality of life in clinical trials 3. Sample sizes for randomized trials measuring quality of life 4. Cross-cultural issues in the use of quality of life measures in randomized controlled trials 5. Profile versus utility based measures of outcome for clinical trials Part III: Decision theory and preference assessment 6. Introduction to decision theory and utilities 7. Using decision theory in clinical research: applications of quality-adjusted life-years 8. Possibilities for summarizing health-related quality of life when using a profile instrument Part IV: Psychometry 9. Questionnaire scaling: models and issues 10. Assessing reliability and validity of measurement in clinical trials 11. Item response theory models 12. Factor analysis Part V: Data analysis 13. Methods of analysis for longitudinal studies of health-related quality of life 14. Analysis of incomplete quality of life data in clinical trials 15. Using the Q-TWiST method for treatment comparisons in clinical trials Part VI: Interpreting and reporting results of QoL clinical trials 16. Clinical interpretation of health-related quality of life data 17. Summarizing quality of life data using graphical methods 18. Guidelines for reporting results of quality of life assessments in clinical trials
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Holdings
Item type Current library Call number Copy number Status Date due Barcode
Book Open Access Book Open Access Health Sciences Library W 20.55.C5 Q15 1998 (Browse shelf(Opens below)) 1 Available MBAL22031810

Includes bibliographical references and index.

Contents

Part I: Introduction
1. Understanding and using health-related quality of life instruments within clinical research studies

Part II: Primary issues specific to quality of life trials
2. Guidelines for measuring health-related quality of life in clinical trials
3. Sample sizes for randomized trials measuring quality of life
4. Cross-cultural issues in the use of quality of life measures in randomized controlled trials
5. Profile versus utility based measures of outcome for clinical trials

Part III: Decision theory and preference assessment
6. Introduction to decision theory and utilities
7. Using decision theory in clinical research: applications of quality-adjusted life-years
8. Possibilities for summarizing health-related quality of life when using a profile instrument

Part IV: Psychometry
9. Questionnaire scaling: models and issues
10. Assessing reliability and validity of measurement in clinical trials
11. Item response theory models
12. Factor analysis

Part V: Data analysis
13. Methods of analysis for longitudinal studies of health-related quality of life
14. Analysis of incomplete quality of life data in clinical trials
15. Using the Q-TWiST method for treatment comparisons in clinical trials

Part VI: Interpreting and reporting results of QoL clinical trials
16. Clinical interpretation of health-related quality of life data
17. Summarizing quality of life data using graphical methods
18. Guidelines for reporting results of quality of life assessments in clinical trials

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