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Bone metastasis and molecular mechanisms : pathophysiology / edited by Gurmit Singh and William Orr.

Contributor(s): Series: Cancer metastasis ; v. 6Publication details: Dordrecht ; Boston : Kluwer Academic, 2004.Description: xvi, 308 p. : ill. ; 25 cmISBN:
  • 140201984X
Subject(s): LOC classification:
  • QZ 203 B712 2004
Online resources:
Contents:
Contents Chapter 1............................. .........................1 Models of Breast Cancer Metastasis to Bone: Characterization of a Clinically Relevant Model Belinda S. Parker, Bederich L. Eckhardt and Robin L. Anderson Chapter 2 ..... ....................... ........................19 Quantitation of Bone Metastasis in Experimental Systems Julie A. Sharp and Erik W. Thompson Chapter 3 ................................................31 Comparative Morphometric Study on Bone Remodeling in Human Specimens and in Experimental Models of Metastatic Bone Disease Snezana Vukmirovic-Popovic, Eric Seidlitz, F. William Orr and Gurmit Singh Chapter 4 .................................................... 49 Clinical Modalities for the Diagnosis, Characterization and Detection of Bone Metastases Michael H. Weber, Jonathan C. Sharp, Thomas H. Hassard, Martin Reed, James A. Thliveris and F. William Orr Chapter 5 ..................................................................71 Metastasis in the Bone Marrow Microenviroment Paolo Bianco, Mara Riminucci and Pamela Gehron Robey Chapter 6 ...... ........... ..................................87 The Role of Tumor-Associated Macrophages in Metastasis- Associated Osteolysis Nicholas. A. Athanasou Chapter 7 .................. ...............................109 The Malignant Hierarchy in Multiple Myeloma: Relationships between Malignant Cells and Bone Disease Linda M. Pilarski, Tony Reiman, Patrick M. Pilarski, F. William Orr and Andrew R. Belch Chapter 8 ................... .............................139 Angiogenesis and Lymphangiogenesis in Metastatic Bone Disease: A Matter of Networking Gabri Van Der Pluijm, and Jereon Buijs Chapter 9 .................... ... ... ..........................163 Prostate Cancer: Models for Developing Novel Therapeutic Approaches Shafaat A. Rabbani, Nicholas Shukeir and Andrew P. Mazar Chapter 10 . ...................... ...................187 Potential Therapeutic Targets for Bone Metastasis Sadmeet Singh and Gurmit Singh Chapter 11 .... ..... ......................................... 211 OPG, RANK and RANKL in Bone Metastasis and Cancer- Associated Osteolysis Paul J. Kostnuik Chapter 12...................... ................................ 241 Role of Matrix Metalloproteinases in Bone Metastasis from Human Breast and Prostate Cancer Wilhelmina C.M Duivendoorden and Gurmit Singh Chapter 13 ... .................... ..................... ..277 The Role of Bisphosphonates in Bone Metastasis Mary Mackenzie and Pierre Major
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Item type Current library Call number Copy number Status Date due Barcode
Book Open Access Book Open Access Health Sciences Library QZ 203 B712 2004 (Browse shelf(Opens below)) 1 Available MBAL22021633

Includes bibliographical references and index.

Contents

Chapter 1............................. .........................1
Models of Breast Cancer Metastasis to Bone:
Characterization of a Clinically Relevant Model
Belinda S. Parker, Bederich L. Eckhardt and Robin L. Anderson

Chapter 2 ..... ....................... ........................19
Quantitation of Bone Metastasis in Experimental Systems
Julie A. Sharp and Erik W. Thompson

Chapter 3 ................................................31
Comparative Morphometric Study on Bone Remodeling in
Human Specimens and in Experimental Models of
Metastatic Bone Disease
Snezana Vukmirovic-Popovic, Eric Seidlitz, F. William Orr and
Gurmit Singh

Chapter 4 .................................................... 49
Clinical Modalities for the Diagnosis, Characterization and
Detection of Bone Metastases
Michael H. Weber, Jonathan C. Sharp, Thomas H. Hassard,
Martin Reed, James A. Thliveris and F. William Orr

Chapter 5 ..................................................................71
Metastasis in the Bone Marrow Microenviroment
Paolo Bianco, Mara Riminucci and Pamela Gehron Robey

Chapter 6 ...... ........... ..................................87
The Role of Tumor-Associated Macrophages in Metastasis-
Associated Osteolysis
Nicholas. A. Athanasou

Chapter 7 .................. ...............................109
The Malignant Hierarchy in Multiple Myeloma:
Relationships between Malignant Cells and Bone Disease
Linda M. Pilarski, Tony Reiman, Patrick M. Pilarski, F. William
Orr and Andrew R. Belch

Chapter 8 ................... .............................139
Angiogenesis and Lymphangiogenesis in Metastatic Bone
Disease: A Matter of Networking
Gabri Van Der Pluijm, and Jereon Buijs

Chapter 9 .................... ... ... ..........................163
Prostate Cancer: Models for Developing Novel Therapeutic
Approaches
Shafaat A. Rabbani, Nicholas Shukeir and Andrew P. Mazar

Chapter 10 . ...................... ...................187
Potential Therapeutic Targets for Bone Metastasis
Sadmeet Singh and Gurmit Singh

Chapter 11 .... ..... ......................................... 211
OPG, RANK and RANKL in Bone Metastasis and Cancer-
Associated Osteolysis
Paul J. Kostnuik

Chapter 12...................... ................................ 241
Role of Matrix Metalloproteinases in Bone Metastasis from
Human Breast and Prostate Cancer
Wilhelmina C.M Duivendoorden and Gurmit Singh

Chapter 13 ... .................... ..................... ..277
The Role of Bisphosphonates in Bone Metastasis
Mary Mackenzie and Pierre Major

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