Bone metastasis and molecular mechanisms : pathophysiology /
Bone metastasis and molecular mechanisms : pathophysiology /
edited by Gurmit Singh and William Orr.
- Dordrecht ; Boston : Kluwer Academic, 2004.
- xvi, 308 p. : ill. ; 25 cm.
- Cancer metastasis-biology and treatment ; v. 6 .
- Cancer metastasis ; v. 6 .
Includes bibliographical references and index.
Contents
Chapter 1............................. .........................1
Models of Breast Cancer Metastasis to Bone:
Characterization of a Clinically Relevant Model
Belinda S. Parker, Bederich L. Eckhardt and Robin L. Anderson
Chapter 2 ..... ....................... ........................19
Quantitation of Bone Metastasis in Experimental Systems
Julie A. Sharp and Erik W. Thompson
Chapter 3 ................................................31
Comparative Morphometric Study on Bone Remodeling in
Human Specimens and in Experimental Models of
Metastatic Bone Disease
Snezana Vukmirovic-Popovic, Eric Seidlitz, F. William Orr and
Gurmit Singh
Chapter 4 .................................................... 49
Clinical Modalities for the Diagnosis, Characterization and
Detection of Bone Metastases
Michael H. Weber, Jonathan C. Sharp, Thomas H. Hassard,
Martin Reed, James A. Thliveris and F. William Orr
Chapter 5 ..................................................................71
Metastasis in the Bone Marrow Microenviroment
Paolo Bianco, Mara Riminucci and Pamela Gehron Robey
Chapter 6 ...... ........... ..................................87
The Role of Tumor-Associated Macrophages in Metastasis-
Associated Osteolysis
Nicholas. A. Athanasou
Chapter 7 .................. ...............................109
The Malignant Hierarchy in Multiple Myeloma:
Relationships between Malignant Cells and Bone Disease
Linda M. Pilarski, Tony Reiman, Patrick M. Pilarski, F. William
Orr and Andrew R. Belch
Chapter 8 ................... .............................139
Angiogenesis and Lymphangiogenesis in Metastatic Bone
Disease: A Matter of Networking
Gabri Van Der Pluijm, and Jereon Buijs
Chapter 9 .................... ... ... ..........................163
Prostate Cancer: Models for Developing Novel Therapeutic
Approaches
Shafaat A. Rabbani, Nicholas Shukeir and Andrew P. Mazar
Chapter 10 . ...................... ...................187
Potential Therapeutic Targets for Bone Metastasis
Sadmeet Singh and Gurmit Singh
Chapter 11 .... ..... ......................................... 211
OPG, RANK and RANKL in Bone Metastasis and Cancer-
Associated Osteolysis
Paul J. Kostnuik
Chapter 12...................... ................................ 241
Role of Matrix Metalloproteinases in Bone Metastasis from
Human Breast and Prostate Cancer
Wilhelmina C.M Duivendoorden and Gurmit Singh
Chapter 13 ... .................... ..................... ..277
The Role of Bisphosphonates in Bone Metastasis
Mary Mackenzie and Pierre Major
140201984X
Bone metastasis.
Cancer--Pathophysiology.
Cancer--Molecular aspects.
QZ 203 B712 2004
Includes bibliographical references and index.
Contents
Chapter 1............................. .........................1
Models of Breast Cancer Metastasis to Bone:
Characterization of a Clinically Relevant Model
Belinda S. Parker, Bederich L. Eckhardt and Robin L. Anderson
Chapter 2 ..... ....................... ........................19
Quantitation of Bone Metastasis in Experimental Systems
Julie A. Sharp and Erik W. Thompson
Chapter 3 ................................................31
Comparative Morphometric Study on Bone Remodeling in
Human Specimens and in Experimental Models of
Metastatic Bone Disease
Snezana Vukmirovic-Popovic, Eric Seidlitz, F. William Orr and
Gurmit Singh
Chapter 4 .................................................... 49
Clinical Modalities for the Diagnosis, Characterization and
Detection of Bone Metastases
Michael H. Weber, Jonathan C. Sharp, Thomas H. Hassard,
Martin Reed, James A. Thliveris and F. William Orr
Chapter 5 ..................................................................71
Metastasis in the Bone Marrow Microenviroment
Paolo Bianco, Mara Riminucci and Pamela Gehron Robey
Chapter 6 ...... ........... ..................................87
The Role of Tumor-Associated Macrophages in Metastasis-
Associated Osteolysis
Nicholas. A. Athanasou
Chapter 7 .................. ...............................109
The Malignant Hierarchy in Multiple Myeloma:
Relationships between Malignant Cells and Bone Disease
Linda M. Pilarski, Tony Reiman, Patrick M. Pilarski, F. William
Orr and Andrew R. Belch
Chapter 8 ................... .............................139
Angiogenesis and Lymphangiogenesis in Metastatic Bone
Disease: A Matter of Networking
Gabri Van Der Pluijm, and Jereon Buijs
Chapter 9 .................... ... ... ..........................163
Prostate Cancer: Models for Developing Novel Therapeutic
Approaches
Shafaat A. Rabbani, Nicholas Shukeir and Andrew P. Mazar
Chapter 10 . ...................... ...................187
Potential Therapeutic Targets for Bone Metastasis
Sadmeet Singh and Gurmit Singh
Chapter 11 .... ..... ......................................... 211
OPG, RANK and RANKL in Bone Metastasis and Cancer-
Associated Osteolysis
Paul J. Kostnuik
Chapter 12...................... ................................ 241
Role of Matrix Metalloproteinases in Bone Metastasis from
Human Breast and Prostate Cancer
Wilhelmina C.M Duivendoorden and Gurmit Singh
Chapter 13 ... .................... ..................... ..277
The Role of Bisphosphonates in Bone Metastasis
Mary Mackenzie and Pierre Major
140201984X
Bone metastasis.
Cancer--Pathophysiology.
Cancer--Molecular aspects.
QZ 203 B712 2004