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Gene therapy of cancer / edited by Peter Walden . . . [et al.] ; assistant editor, Patricia Zambon.

Contributor(s): Series: Advances in experimental medicine and biology ; v. 451Publication details: New York : Plenum Press, c1998.Description: xvi, 568 p. : ill. ; 27 cmISBN:
  • 9780306460272
  • 0306460270
Subject(s): DDC classification:
  • 616.9940426 21 GEN
Online resources:
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Holdings
Item type Current library Call number Copy number Status Date due Barcode
Book Open Access Book Open Access Engineering Library 616.9940426 GEN 1 (Browse shelf(Opens below)) 1 Available 0025343

Contents;

Tumor biology
1. Expression genetics in cancer research, prognosis and therapy
2. Patterns of chromosomal imbalances in carcinomas of the respiratory tract
3. Inhibition of tumorigenesis in murine B-cell lymphoma transplant model
4. Telomerase inhibition by induced expression of antisense RNA
5. Ex vivo and in vivo IGF-I antisense RNA strategies for treatment of cancer in humans
etc.

Chemogene therapy
16. Intratumoral injection of encapsulated cells producing an oxazaphosphorine activating cytochrome P450 for targeted chemotherapy
17. Sensitisation of human ovarian cancer cells to killing by the prodrug CB1954 following retroviral or adenoviral transfer of the E.
18. HSV-1 thymidine kinase gene therapy for peritoneal carcinomatosis
19. Characteristics of cytosine deaminase-5-fluorocytosine system: Enhancement of radiation cytotoxicity and bystander effect
20. Potentiation of the bystander effect by immunization combined with suicide gene therapy
etc.

Tumor immunology
26. Overcoming T cell ignorance by providing costimulation: Implications for the immune response against cancer
27. Immune cells in the tumor micorenvironment: Mechanisms responsible for functional and signaling defects
28. Dendritic cells prevent CD95 mediated T lymphocyte death through costimulatory signals
29. Interleukin-10 inhibits the immune stimulatory potential of melanoma cells retrovirally tansduced with human
30. Immunosuppressive cells in bone marrow of patients with stomach cancer
etc.

Immunogene therapy
40. Human tumor immunotherapy: New opportunities as well as new challenges
41. Modification of cancer vaccines by virus infection and attachment of bispecific antibodies: An effective alternative to somatic gene therapy
42. Immunotherapy of established tumor with MHC class II and B7.1 cell-based tumor vaccines
43. Retroviral B7.1 gene transfer in cancer cells protects cytotoxic T cells from deletion by Vero apoptosis
44. Hybrid cell vaccination in cancer immunotherapy: Recruitment and activation of T cell help for induction of anti tumour cytotoxic T cells
etc.


Includes bibliographical references and indexes.

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