The mechanics of inheritance / Franklin W. Stahl

Content

HEREDITY
Microorganisms in genetic research
The growth of bacterial cultures
Mutation in bacterial cultures
Measurement of mutation rate
Mutations and enzymes
Summary
References
Problems

IDENTIFICATION OF THE GENIC MATERIAL
Bacterial transformation
Identification of the transforming agent
The life cycle of bacteriophage
Summary
References
Problems

THE STRUCTURE OF DNA (AND RNA)
The deoxyribonucleotides
DNA chains
DNA molecules
The rare deoxyribonucleotides
The structure of viral RNA
Summary
References
Problems

DUPLICATION OF DNA
Semiconservative transmission" of isotopic label
In vitro synthesis of DNA
Duplication of single-chained genic materials
Summary
References
Problems

MUTATION OF DNA
Tautomerism of bases
Mutation by base-pair transitions
Base pair transition induced by 5-bromouracil and nitrous acid
Other mutations in DNA
Summary
References
problems

ORGANIZATION OF DNA

Packing of DNA
The phage chromosome
The bacterial chromosome
Chromosomes of higher organisms
Summary References
Problems

RECOMBINATION IN HIGHER ORGANISMS
Meiosis
Segregation
Recombination
Crossing over
The mapping function
Departures from the ideal mapping function
Three-factor crosses
A formal model for recombination
Nonreciprocal recombination
Summary
References
Problems

RECOMBINATION IN VIRUSES
A phage cross
The mating theory
The linear mapping function
Correspondence between map and chromosome
Circular maps
High negative interference and "heterozygotes"
Fine-structure analysis
Recombination in RNA viruses
Summary
References
Problems

RECOMBINATION BACTERIA
Phages and bacterial chromosomes
Transduction
Episomes in bacterial fertility
The "mechanism " of recombination in bacteria
Summary
References
Problems

THE GENETIC ANALYSIS OF DIPLOIDS
Genotype and phenotype
Phenotypic lag and phenotypic mixing
Dominance and recessiveness
Nature and nurture
Complementation
Heterozygosis in bacteria
Diploidy in higher organisms
Reference
Problem

Includes bibliographies.