Rogers' textbook of pediatric intensive care / editor, David G. Nichols ; section editors, Alice D. Ackerman ... [et al.].

Includes bibliographical references and index.

Table of contents
Part One: Critical Care Integration
Section I
Introduction to the Practice of Pediatric Critical Care
Section Editor: David G. Nichols and Edwin van der Voort
Chapter 1 The History of Pediatric Intensive Care Around the World 00
Mark C. Rogers
Chapter 2 Pediatric Intensive Care: A Global Perspective 00
Trevor Duke, Niranjan "Tex" Kissoon, Edwin van der Voort
Chapter 3 Impact of Pediatric Critical Care on the Family, Community, and Society 00
Lewis H. Romer, David G. Nichols, Heather Woods Barthel, Jos M. Latour, Jessica Mesman
Section II
Professionalism, Leadership, and Systems-Based Practice
Section Editor: Alice D. Ackerman, Andrew Argent, and Murray M. Pollack
Chapter 4 Professionalism, Simulation Training, and Leadership in Pediatric Critical Care 00
Alice D. Ackerman, Elizabeth A. Hunt, Vinay M. Nadkarni
Chapter 5 Physical Design and Personnel Organization of the PICU 00
M. Michele Moss, Shari Simone
Chapter 6 Practice Management: The Business of Pediatric Critical Care 00
Alice D. Ackerman, A. Marc Harrison
Chapter 7 Research Design and Statistical Analysis 00
Wynne E. Morrison, Elizabeth A. Hunt, Anne-Marie Guerguerian
Chapter 8 Evidence-Based Medicine 00
Barry P. Markovitz, Kathleen L. Meert
Chapter 9 Severity of Illness Scoring Systems 00
Murray Pollack
Chapter 10 Quality Improvement, Patient Safety, and Medical Error 00
Andrew C. Argent, Vicki L. Montgomery
Chapter 11 Information Technology in the PICU 00
Vinay Vaidya, Steven Pon

Section III
Ethical and Compassionate Care of the Critically Ill Child
Section Editor: Robert Truog and Myron Yaster
Chapter 12 Pain and Sedation Management in the Critically Ill Child 00
Myron Yaster, R. Blaine Easley, Kenneth M. Brady
Chapter 13 Rehabilitation of Children With Critical Illness 00
Melissa K. Trovato, Frank S. Pidcock, Cristina Sadowsky, Ewa B. Brandys, Stacy J. Suskauer, Cynthia F.
Salorio, James R. Christensen
Chapter 14 Ethics 00
George E. Hardart, Denis J. Devictor, Robert D. Truog
Chapter 15 Organ Donation 00
Kristin L. Nelson, Ivor D. Berkowitz
Section IV
Basic Concepts of Pediatric Critical Care
Section Editor: Hector R. Wong
Chapter 16 Genomic Medicine 00
Mary K. Dahmer, Michael Quasney
Chapter 17 Innate Immunity and Inflammation 00
James A. Thomas
Chapter 18 Cellular Adaptations to Stress 00
Derek S. Wheeler, Hector R. Wong
Chapter 19 Shock and Reperfusion Injury 00
Basilia Zingarelli
Chapter 20 Pharmacology 00
Athena F. Zuppa, Jeffrey S. Barrett
Chapter 21 Multiple Organ Dysfunction Syndrome 00
Yong Y. Han, Thomas P. Shanley
Part Two: Emergency Care and Acute Management
Section I
Initial Stabilization
Section Editor: Vinay M. Nadkarni and Niranjan "Tex" Kissoon
Chapter 22 Airway Management 00
Allan de Caen, Jonathan Duff, Ashraf H. Coovadia, Robert Luten, Ann E. Thompson, Mary Fran Hazinski
Chapter 23 Pediatric Cardiopulmonary Resuscitation 00
Robert A. Berg, Katsuyuki Miyasaka, Antonio Rodriguez-Nuñez, Mary Fran Hazinski, David Zideman, Vinay
M. Nadkarni
Chapter 24 Transport 00
Monica E. Kleinman, Aaron J. Donoghue, Richard A. Orr, Niranjan "Tex" Kissoon
Chapter 25 Invasive Procedures 00
Stephen M. Schexnayder, Praveen Khilnani, Naoki Shimizu, Arno L. Zaritsky
Chapter 26 Recognition and Initial Management of Shock 00
Simon Nadel, Niranjan "Tex" Kissoon, Suchitra Ranjit
Section II
Environmental Crises
Section Editor: Charles L. Schleien
Chapter 27 Multiple Trauma 00
John Scott Baird, Arthur Cooper
Chapter 28 Drowning and Near Drowning: Submersion Injuries 00
Katherine Biagas
Chapter 29 Burns, Electrical Injuries, and Smoke Inhalation 00
Roger W. Yurt, Joy D. Howell, Bruce M. Greenwald
Chapter 30 Terrorism and Mass Casualty Events 00
Philip L. Graham, III, George L. Foltin, F. Meridith Sonnett
Chapter 31 Poisoning 00
G. Patricia Cantwell, Richard S. Weisman
Chapter 32 Thermoregulation 00
Pamela Feuer, Thyyar M. Ravindranath, David G. Nichols
Chapter 33 Envenomation Syndromes 00
James Tibballs, Kenneth D. Winkel
Section III
Life-Support Technologies
Section Editor: Heidi J. Dalton and Jacques Lacroix
Chapter 34 Mechanical Ventilation 00
Mark J. Heulitt, Gerhard K. Wolf, John H. Arnold
Chapter 35 Inhaled Gases 00
Angela T. Wratney, Donna S. Hamel, Ira M. Cheifetz
Chapter 36 Extracorporeal Life Support 00
Steven A. Conrad, Heidi J. Dalton
Chapter 37 Renal Replacement Therapies 00
Warwick W. Butt, Peter W. Skippen, Phillippe Jouvet
Chapter 38 Blood Products in the PICU 00
Jacques Lacroix, Naomi L.C. Luban, Edward C.C. Wong
Chapter 39 Plasmapheresis and Transfusion Therapy 00
Peter W. Skippen, Niranjan "Tex" Kissoon, Caron Strahlendorf, Warwick W. Butt
Part Three: Critical Care Organ Systems
Section I
Respiratory Disease
Section Editor: Randall C. Wetzel
Chapter 40 The Molecular Biology of Acute Lung Injury 00
Todd Carpenter, R. Blaine Easley, Kurt R. Stenmark
Chapter 41 Respiratory Physiology 00
Frank L. Powell, Gregory P. Heldt, Gabriel G. Haddad
Chapter 42 Respiratory Monitoring 00
Ira M. Cheifetz, Shekhar T. Venkataraman, Donna S. Hamel
Chapter 43 Status Asthmaticus 00
Michael Bigham, Richard J. Brilli
Chapter 44 Neonatal Respiratory Failure 00
Elisabeth L. Raab, Lisa K. Kelly, Philippe S. Friedlich, Rangasamy Ramanathan, Istvan Seri
Chapter 45 Bronchiolitis and Pneumonia 00
Marcelo Cunio Machado Fonseca, Cíntia Johnston, Werther Brunow de Carvalho
Chapter 46 Acute Lung Injury and Acute Respiratory Distress Syndrome 00
Kathleen M. Ventre, John H. Arnold
Chapter 47 Chronic Respiratory Failure 00
Thomas G. Keens, Sheila S. Kun, Sally L. Davison Ward
Chapter 48 Sleep and Breathing 00
Sally L. Davison Ward, Thomas G. Keens
Section II
Neuromuscular Disease
Section Editor: Donald H. Shaffner
Chapter 49 Acute Neuromuscular Disease 00
Sunit C. Singhi, Alka Khadwal, Arun Bansal
Chapter 50 Chronic Neuromuscular Disease 00
Jonathan Gillis, Monique M. Ryan
Section III
Neurologic Disease
Section Editor: Robert C. Tasker and Patrick M. Kochanek
Chapter 51 Developmental Neurobiology, Neurophysiology, and the PICU 00
Larry W. Jenkins, Patrick M. Kochanek
Chapter 52 Molecular Biology of Brain Injury 00
Patrick M. Kochanek, Hülya Bayir, Larry W. Jenkins, Robert S.B. Clark
Chapter 53 Evaluation of the Comatose Child 00
Nicholas S. Abend, Sudha Kilaru V. Kessler, Mark A. Helfaer, Daniel J. Licht
Chapter 54 Neurologic Monitoring 00
Brahm Goldstein, Mateo Aboy, Alan Graham
Chapter 55 Neurologic Imaging 00
David Joshua Michelson, Stephen Ashwall
Chapter 56 Head and Spinal Cord Trauma 00
Robert C. Tasker
Chapter 57 Status Epilepticus 00
Kimberly D. Statler, Colin B. Van Orman
Chapter 58 Cerebrovascular Disease and Stroke 00
John Pappachan, Fenella Kirkham
Chapter 59 Hypoxic-Ischemic Encephalopathy 00
Ericka L. Fink, Mioara D. Manole, Robert S.B. Clark
Chapter 60 Metabolic Encephalopathies in Children 00
Phillippe Jouvet, Anne Lortie, Bruno Maranda, Robert C. Tasker
Chapter 61 Brain Death 00
Daniel L. Levin
Section IV
Cardiac Disease
Section Editor: Duncan Macrae, Keith C. Kocis, and David G. Nichols
Chapter 62 Cardiac Anatomy 00
Steven M. Schwartz, Zdenek Slavik, Siew Yen Ho
Chapter 63 Cardiovascular Physiology 00
Peter E. Oishi, David F. Teitel, Julien I. Hoffman, Jeffrey R. Fineman
Chapter 64 Cardiorespiratory Interactions in Children with Heart Disease 00
R. Lara Shekerdemian
Chapter 65 Hemodynamic Monitoring 00
Gillian C. Halley, Shane Tibby
Chapter 66A Heart Failure in Infants and Children: Etiology, Pathophysiology, and Diagnosis of Heart Failure
00
Jeffrey J. Kim, Joseph W. Rossano, David P. Nelson, Jack F. Price, William J. Dreyer
Chapter 66B Heart Failure in Infants and Children: Cardiomyopathy 00
John Lynn Jefferies, Susan W. Denfield, William J. Dreyer
Chapter 66C Heart Failure in Infants and Children: Myocarditis 00
John Philip Breinholt III, David P. Nelson, Jeffrey A. Towbin
Chapter 67A Treatment of Heart Failure in Infants and Children: Medical Management 00
Joseph W. Rossano, Jack F. Price, David P. Nelson
Chapter 67B Treatment of Heart Failure in Infants and Children: Mechanical Support 00
Ana Lia Graciano, Jon N. Meliones, Keith C. Kocis
Chapter 67C Treatment of Heart Failure in Infants and Children: Cardiac Transplantation 00
Steven A. Webber
Chapter 68 Cardiac Conduction, Dysrhythmias, and Pacing 00
Bradley S. Marino, Jonathan R. Kaltman, Ronn E. Tanel
Chapter 69 Preoperative Care of the Pediatric Cardiac Surgical Patient 00
David L. Wessel, Alan Fraisse
Chapter 70A Postoperative Care of the Pediatric Cardiac Surgical Patient: General Considerations
00
David L. Wessel, Alan Fraisse
Chapter 70B Postoperative Care of the Pediatric Cardiac Surgical Patient: Lesion-Specific Management
00
Steven M. Schwartz, Johnny Millar
Chapter 70C Postoperative Care of the Pediatric Cardiac Surgical Patient: Effects of Cardiopulmonary Bypass
00
S. Adil Husain, Mark S. Bleiweis
Section V
Immunologic Diseases
Section Editor: Joseph A. Carcillo and Hans-Dieter Volk
Chapter 71 Neurohormonal Control in the Immune System 00
Kathryn A. Felmet
Chapter 72 The Immune System 00
Meredith L. Allen, Nigel J. Klein, Mark J. Peters
Chapter 73 The Polymorphonuclear Leukocyte in Critical Illness 00
M. Michele Mariscalco
Chapter 74 The Immune System and Viral Illness in the Critically Ill 00
Lesley Doughty
Chapter 75 Immune Modulation and Immunotherapy in Critical Illnesss 00
Mark W. Hall
Chapter 76 Immunology of Cancer and Primary Immune Deficiency Syndromes 00
Brandt P. Groh, Jennifer A. McArthur, Sachin S. Jogal, Robert F. Tamburro
Section VI: Infectious Diseases
Section Editor: Alice D. Ackerman and Sunit Singhi
Chapter 77 Principles of Anti-microbial Therapy 00
Philip Toltzis, Jeffrey L. Blumer
Chapter 78 Bacterial Sepsis and Mechanisms of Microbial Pathogenesis 00
Neal J. Thomas, Robert F. Tamburro, Mark W. Hall, Surender Rajasekaran, John S. Venglarcik, III
Chapter 79 Critical Viral Infections 00
Rakesh Lodha, Sunit C. Singhi, James D. Campbell
Chapter 80 Central Nervous System Infections 00
Pratibha D. Singhi, Sunit C. Singhi, Charle RJC Newton, Jakub Simon
Chapter 81 Nosocomial Infections 00
John P. Straumanis
Chapter 82 International and Emerging Infections 00
Troy E. Dominguez, Chitra Ravishankar, Miriam K. Laufer
Chapter 83 Toxin-related Diseases 00
Sunit C. Singhi, M. Jayashree, John P. Straumanis, Karen L. Kotloff
Chapter 84 Opportunistic Infections 00
Sushil K. Kabra, Matthew B. Laurens
Section VII: Nutritional and Gastrointestinal Disorders
Section Editor: Donald H. Shaffner and Z. Leah Harris
Chapter 85 Principles of Nutrition and Metabolism 00
Muraya Gathinji, Z. Leah Harris
Chapter 86 Nutritional Support in the Critically Ill Child 00
Werther Brunow de Carvalho, Heitor Pons Leite
Chapter 87 The Acute Abdomen 00
Eduardo Schnitzler, Tomas Iölster, Daniel Russo
Chapter 88 Fulminant Hepatic Failure and Transplantation 00
Pierre Tissières, Denis J. Devictor, Geoffrey J. Bond
Chapter 89 Intestinal and Multivisceral Transplantation 00
Kathryn A. Felmet, Ronald Jaffe, Kyle A. Soltys, Robert H. Squires, Jr., Dolly Martin, Rakesh Sindhi, Kareem
Abu-Elmagd, George V. Mazariegos
Chapter 90 Critical Aspects of Intestinal Disorders 00
Aristides Baltodano, Mehrengise K. Cooper
Section VIII
Renal, Endocrine, and Metabolic Disorders
Section Editor: Katherine Biagas and Charles L. Schleien
Chapter 91 Adrenal Dysfunction 00
Sharon E. Oberfield, Abeer Hassoun
Chapter 92 Disorders of Glucose Homeostasis 00
Stuart A. Weinzimer, Michael F. Canarie, Edward Vincent S. Faustino, William V. Tamborlane, Clifford W.
Bogue
Chapter 93 Disorders of Water, Sodium, and Potassium Homeostasis 00
Andrea Kelly, Thomas Moshang, Jr.
Chapter 94 Disorders of Calcium, Magnesium, and Phosphate 00
Kenneth J. Banasiak, Thomas O. Carpenter
Chapter 95 Thyroid Disease 00
Ori Eyal, Susan R. Rose
Chapter 96 Acute Renal Failure and End-stage Renal Disease 00
Richard Hackbarth, Norma Maxvold, Timothy E. Bunchman
Chapter 97 Hypertensive Crises 00
George Ofori-Amanfo, Arthur Smerling
Chapter 98 Inborn Errors of Metabolism 00
Michael Wilhelm, Wendy K. Chung
Section IX: Oncologic and Hematologic Disorders
Section Editor: Charles L. Schleien and David G. Nichols
Chapter 99 Cancer Therapy: Mechanisms, Toxicities, and Ethics in the PICU 00
David M. Loeb, David G. Nichols
Chapter 100 Oncologic Emergencies and Complications 00
Rodrigo Mejia, Jose A. Cortes, Deborah L. Brown, Gerardo Quezada, Michael E. Rytting, Carroll J. King, Alan
I. Fields
Chapter 101 Hematologic Emergencies 00
R. Blaine Easley, Kenneth M. Brady, Joseph D. Tobias
Chapter 102 Bone Marrow and Stem Cell Transplantation 00
Katherine Biagas, M. Brigid Bradley, Mitchell S. Cairo
Chapter 103 Coagulation Disorders 00
Robert I. Parker, Jan A. Hazelzet
Chapter 104 Sickle Cell Disease 00
Kevin J. Sullivan, Niranjan "Tex" Kissoon, Salvatore R. Goodwin