Non-viral vectors for gene therapy / edited by Leaf Huang, Mien-chie Hung, Ernst Wagner.

Contributor(s): Material type: TextTextSeries: Advances in genetics ; v. 53-54Publication details: Amsterdam ; Boston : Elsevier Academic Press, c2005.Edition: 2nd edition : part IDescription: 2 v. : ill. (some col.) ; 24 cmISBN:
  • 012017653X (pt. 1)
  • 9780120176533
Other title:
  • Nonviral vectors for gene therapy
Subject(s): DDC classification:
  • 22 616.042 NON
Online resources:
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Holdings
Item type Current library Call number Copy number Status Date due Barcode
Book Open Access Book Open Access Health Sciences Library 616.042 NON 1 (Browse shelf(Opens below)) 1 Available MBAL22010905

Contents

1. Basic concepts
1.Recent Advances in Non-viral Gene Delivery
2.Barriers to gene delivery using synthetic vectors
3.Pharmacokinetics of Plasmid DNA-Based Nonviral Gene Medicine

2.Cationic Liposomes
4.What Role can chemistry play in cationic liposome-based gene therapy research today?
5.Lipoplex structures and their distinct cellular pathways
6. Diffusible-PEG-Lipid stabilized plasmid lipid particles
7.Toxicity of Catonic lipid-DNA complexes

3. Cationic Polymers
8.Polyethylenimine (PEI)
9.Pluronic Block Copolymers for gene delivery
10.Terplex gene delivery system
11.Design of polyphosphoester-DNA nanoparticles for nonviral gene delivery
12.Development of HVJ envelope vector and its application to gene therapy
13.Targeting of polyplexes: towards synthetic virus vector systems.

Includes bibliographical references and indexes.

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