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Non-viral vectors for gene therapy / Nonviral vectors for gene therapy edited by Leaf Huang, Mien-chie Hung, Ernst Wagner. - 2nd edition : part I - Amsterdam ; Boston : Elsevier Academic Press, c2005. - 2 v. : ill. (some col.) ; 24 cm. - Advances in genetics ; v. 53-54 .

Includes bibliographical references and indexes.

Contents

1. Basic concepts
1.Recent Advances in Non-viral Gene Delivery
2.Barriers to gene delivery using synthetic vectors
3.Pharmacokinetics of Plasmid DNA-Based Nonviral Gene Medicine

2.Cationic Liposomes
4.What Role can chemistry play in cationic liposome-based gene therapy research today?
5.Lipoplex structures and their distinct cellular pathways
6. Diffusible-PEG-Lipid stabilized plasmid lipid particles
7.Toxicity of Catonic lipid-DNA complexes

3. Cationic Polymers
8.Polyethylenimine (PEI)
9.Pluronic Block Copolymers for gene delivery
10.Terplex gene delivery system
11.Design of polyphosphoester-DNA nanoparticles for nonviral gene delivery
12.Development of HVJ envelope vector and its application to gene therapy
13.Targeting of polyplexes: towards synthetic virus vector systems.

ISBN: 012017653X (pt. 1) 9780120176533

Subjects--Topical Terms:
Genetic vectors.
Genetic transformation.
Gene therary.
Genetic Vectors--therapeutic use.
Gene Therapy--methods.
Gene Transfer Techniques.
Transformation, Genetic.

Dewey Class. No.: QU 560 N812 2005 / N812 2005