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Applied biopharmaceutics & pharmacokinetics / editors, Leon Shargel & Andrew B.C. Yu.

Contributor(s): Publisher: New York : McGraw-Hill Education, [2016]Edition: 7th editionDescription: xvii, 910 p. : ill. (some col.) ; 24 cmISBN:
  • 9780071830935
  • 0071830936
  • 9789814670241
  • 9814670243
Other title:
  • Applied biopharmaceutics and pharmacokinetics
  • Shargel & Yu's Applied biopharmaceutics and pharmacokinetics [Cover title]
Subject(s): DDC classification:
  • 615.7 23 APP
NLM classification:
  • QV 38
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Holdings
Item type Current library Call number URL Status Date due Barcode
e Book e Book Health Sciences Library 615.7 APP (Browse shelf(Opens below)) Link to resource Available BUML24060262

Contents;

Chapter 1: Introduction to Biopharmaceutics and Pharmacokinetics
Chapter 2: Mathematical Fundamentals in Pharmacokinetics
Chapter 3: Biostatistics
Chapter 4: One-Compartment Open Model: Intravenous Bolus Administration
Chapter 5: Multicompartment Models: Intravenous Bolus Administration

Chapter 6: Intravenous Infusion
Chapter 7: Drug Elimination, Clearance, and Renal Clearance
Chapter 8: Pharmacokinetics of Oral Absorption
Chapter 9: Multiple-Dosage Regimens
Chapter 10: Nonlinear Pharmacokinetics

Chapter 11: Physiologic Drug Distribution and Protein Binding
Chapter 12: Drug Elimination and Hepatic Clearance
Chapter 13: Pharmacogenetics and Drug Metabolism
Chapter 14: Physiologic Factors Related to Drug Absorption

Chapter 15: Biopharmaceutic Considerations in Drug Product Design and In Vitro Drug Product Performance
Chapter 16: Drug Product Performance, In Vivo: Bioavailability and Bioequivalence
Chapter 17: Biopharmaceutical Aspects of the Active Pharmaceutical Ingredient and Pharmaceutical Equivalence
Chapter 18: Impact of Biopharmaceutics on Drug Product Quality and Clinical Efficacy
Chapter 19: Modified-Release Drug Products and Drug Devices

Chapter 20: Targeted Drug Delivery Systems and Biotechnological Products
Chapter 21: Relationship Between Pharmacokinetics and Pharmacodynamics
Chapter 22: Application of Pharmacokinetics to Clinical Situations
Chapter 23: Application of Pharmaco­kinetics to Specific Populations: Geriatric, Obese, and Pediatric Patients
Chapter 24: Dose Adjustment in Renal and Hepatic Disease
Chapter 25: Empirical Models, Mechanistic Models, Statistical Moments, and Noncompartmental Analysis

Includes bibliographical references and index.

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