When cells die : a comprehensive evaluation of apoptosis and programmed cell death / edited by Richard A. Lockshin, Zahra Zakeri, and Jonathan L. Tilly.

Includes bibliographical references and index.

Contents

PART I: THE PHENOMENON OF CELL DEATH.
1.The Evolutionary Origin and Role of Programmed Cell Death in Single-Celled Organisms: A New View at Executioners,
Mitochondria, Host-Pathogen Interactions, and the Role of Death in the Process of Natural Selection (J. Ameisen).
2.The Reactions of Cells to Lethal Injury: Oncosis and Necrosis--The Role of Calcium (B. Trump & I. Berezesky).
3.The Study of Cell Death by the Use of Cellular and Developmental Models (Z. Zakeri).
4.Genetic Approaches to Programmed Cell Death in C. Elegans (A. Gartner & M. Hengartner).
5. Cell Death in Plants (R. Mittler).

PART II: THEMES AND APPROACHES TO CELL DEATH.
6.The Cutting Edge: Caspases in Apoptosis and Disease (V. Cryns & J. Yuan).
7. Endonuclease Activities and Apoptosis (M. Sikorska & P. Walker).

PART III:CELL DEATH WHEN MITOSIS IS HIGH AND EVANESCENCE IS DESIRABLE.
8.Apoptotic Signaling Pathways in Lymphocytes (B. Osborne).
9.Regulation of Immune Responses by Immune Directed Cell Death (M. Newell & M. Vincent).
10.Apoptosis in Autoimmunity (R. Budd).
11. Aids and Cell Death (T. Finkel & C. Casella).

PART IV: CELL DEATH IN LONG-LIVED CELLS.
12.Apoptosis of Tissues of the Eye During Development and Disease (D. Papermaster).
13.Signal Transduction and Neuronal Cell Death During Development and Disease (R. Birge, et al.).
14.Cell Death in Alzheimer's Disease (C. Cotman, et al.).
15.Regulation of Apoptosis by Cellular Interactions with the Extracellular Matrix (J. Tidball & D. Albrecht).

PART V: THE CLINICAL RELEVANCE OF APOPTOSIS.
16.Cell Death and Species Propagation: Molecular and Genetic Aspects of Apoptosis in the Vertebrate Female Gonad (J. Tilly).
17. Assessment of Apoptosis in Tumor Growth: Importance in Clinical Oncology and Cancer Therapy (L. Ben?tez-Bribiesca).