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Combinatorial chemistry : synthesis and application / edited by Stephen R. Wilson, Anthony W. Czarnik.

Contributor(s): Publication details: New York : Wiley, c1997.Description: ix, 269 p. : ill. ; 24 cmISBN:
  • 047112687X (cloth : alk. paper)
  • 9780471126874
Subject(s): DDC classification:
  • QV 744 C731 1997
Online resources:
Contents:
Content 1. Introduction to Combinatorial Libraries:Concepts and Terms 2. Parallel Organic Synthesis Using Parke-Davis Diversomer Technology (S. DeWitt & A. Czarnik). 3. Polymer-Supported Synthesis of Organic Compounds and Libraries (M. Kurth). 4. Macro Beads as Microreactors: New Solid- Phase Synthesis Methodology (W. Rapp). 5. Combinatorial Libraries in Solution: Polyfunctionalized Core Molecules (E. Wintner & J. Rebek). 6. Solid-Phase Methods in Combinatorial Chemistry (I. Sucholeiki). 7. Radiofrequency Encoding and Additional Techniques for the structure Elucidation of Synthetic Combitariol Libraries 8. Combinatorial Synthesis Exploiting Multiple-Component Condensations, Microchip Encoding, and Resin Capture (R. Armstrong, et al.). 9. Indexed Combinatorial Libraries: Nonoligomeric Chemical Diversity for the Discovery of Novel Enzyme Inhibitors (M. Pirrung, et al.). 10. Strategies for Combinatorial Libraries of Oligosaccharides 11. Soluble Combinatorial Libraries of Peptides, Peptidomimetics, and Organics: Fundamental Tools for Basic Research and Drug Discovery 12. Combinatorial Libraries of Peptides, Proteins, and Antibodies Using Biological Systems (S. Benkovic, et al.).
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Includes bibliographical references and index.

Content
1. Introduction to Combinatorial Libraries:Concepts and Terms
2. Parallel Organic Synthesis Using Parke-Davis Diversomer Technology (S. DeWitt & A. Czarnik).
3. Polymer-Supported Synthesis of Organic Compounds and Libraries (M. Kurth).
4. Macro Beads as Microreactors: New Solid- Phase Synthesis Methodology (W. Rapp).
5. Combinatorial Libraries in Solution: Polyfunctionalized Core Molecules (E. Wintner & J. Rebek).
6. Solid-Phase Methods in Combinatorial Chemistry (I. Sucholeiki).
7. Radiofrequency Encoding and Additional Techniques for the structure Elucidation of Synthetic Combitariol Libraries
8. Combinatorial Synthesis Exploiting Multiple-Component Condensations, Microchip Encoding, and Resin Capture (R. Armstrong, et al.).
9. Indexed Combinatorial Libraries: Nonoligomeric Chemical Diversity for the Discovery of Novel Enzyme Inhibitors (M. Pirrung, et al.).
10. Strategies for Combinatorial Libraries of Oligosaccharides
11. Soluble Combinatorial Libraries of Peptides, Peptidomimetics, and Organics: Fundamental Tools for Basic Research and Drug Discovery
12. Combinatorial Libraries of Peptides, Proteins, and Antibodies Using Biological Systems (S. Benkovic, et al.).

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