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Francisella tularensis : biology, pathogenicity, epidemiology, and biodefense / edited by Yousef Abu Kwaik ... [et al.].

Contributor(s): Series: Annals of the New York Academy of Sciences ; v. 1105Publication details: Boston, Mass. : Published by Blackwell Pub. on behalf of the New York Academy of Sciences, 2007.Description: x, 419 p. : ill. ; 23 cmISBN:
  • 9781573316910 (pbk. : alk. paper)
  • 1573316911 (pbk. : alk. paper)
Subject(s): NLM classification:
  • QW 131 F819 2007
Online resources:
Contents:
Tularemia: History, epidemiology, pathogen physiology, and clinical manifestations. 2. Molecular ecology, epidemiology and evolution of Francisella. 3. Genetics and genetic manipulations of F. tularensis. 4. Genomics and metagenomics of F. tularensis. 5. The Francisella pathogenicity Island 6. Molecular and genetic bases of pathogenesis of F. tularensis. 7. Novel entry and trafficking of F. tularensis within macrophages. 8. Type II secretion and type IV pili of Francisella. 9. Phase variation in Francisella tularensis 10. Triggering the inflammasomes by Francisella 11. Animal models of Tularemia 12. Mucosal immunity to Francisella 13. Inflammation, innate and adaptive immunity, and Vaccines to F. tularensis. 14. Tularemia vaccines, past, current, and future. 15. New approaches to diagnosis and therapy of Tularemia 16. Biosafety and selectable markers for Francisella
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Includes bibliographical references and index.

Tularemia: History, epidemiology, pathogen physiology, and clinical manifestations.

2. Molecular ecology, epidemiology and evolution of Francisella.

3. Genetics and genetic manipulations of F. tularensis.

4. Genomics and metagenomics of F. tularensis.

5. The Francisella pathogenicity Island

6. Molecular and genetic bases of pathogenesis of F. tularensis.

7. Novel entry and trafficking of F. tularensis within macrophages.

8. Type II secretion and type IV pili of Francisella.

9. Phase variation in Francisella tularensis

10. Triggering the inflammasomes by Francisella

11. Animal models of Tularemia

12. Mucosal immunity to Francisella

13. Inflammation, innate and adaptive immunity, and Vaccines to F. tularensis.

14. Tularemia vaccines, past, current, and future.

15. New approaches to diagnosis and therapy of Tularemia

16. Biosafety and selectable markers for Francisella

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