The endothelium in clinical practice : source and target of novel therapies /

The endothelium in clinical practice : source and target of novel therapies / edited by Gabor M. Rubanyi, Victor J. Dzau. - New York : M. Dekker, c1997. - xvi, 551 p. : ill. ; 24 cm. - Fundamental and clinical cardiology ; 29 . - Fundamental and clinical cardiology ; v. 29. .

Includes bibliographical references and index.

Content
I. The Endothelium as the Source of Novel Therapies
1. Prostacyclin (Prostaglandin I2) and Atherosclerosis, Karsten Schroer
2. Prostacyclin and Thromboxane: Role in Ischemic Heart Disease, Jawahar L. Mehta and Baichun C. Yang
3. Clinical Use of Prostacyclins, John A. Dormandy and Glyn Belcher
4. Nitric Oxide Synthases: Enzymology and Mechanism-Based Inhibitors, John F. Parkinson and Gary Phillips
5. Endothelin: From Basic to Pathophysiological Research, Katsutoshi Goto
6. Transmigration of Leukocytes, B. Stein, Y. Khew-Goodall, J. Gamble, and M. A. Vadas
7. Transforming Growth Factor-b and Cardiovascular Protection, David J. Grainger and James C. Metcalfe
8. Coagulation Factors, Michael Kalafatis, Jack O. Egan, and Kenneth G. Mann

II. The Endothelium as a Target for Novel Therapies
9. Endothelial Dysfunction and Vascular Disease, Paul M. Vanhoutte, Louis Perrault, and Jean Paul Vilaine
10. Complement and Endothelium: Novel Complement-Inhibitory Therapeutics, Una S. Ryan
11. The Receptor for Advanced Gycation Endproducts: Implications for the, Development of Diabetic Vascular Disease, Osamu Hori, Shi Du Yan, and Ann Marie Schmidt
12. Hypertension, Pierre Moreau and Thomas F. Luscher
13. Arterial Restenosis, Michael A. Reidy and Stephen M. Schwartz
14. Pathobiology and Clinical Consequences of Plaque Rupture, Richard Gallo, Juan J. Badimon, James H. Chesebro, Valentin Fuster, and Lina Badimon
15. Isoprostanes and Antioxidant Therapy in Human Diseases, Emma A. Meagher and Garrett A. FitzGerald
16. Vasculoprotection by Estrogen Contributes to Gender Difference in Cardiovascular Diseases: Potential Mechanism and Role of Endothelium, Katalin Kauser and Gabor M. Rubanyi
17. Lipoprotein(a): Insights from Transgenic Mice, Steven D. Hughes and Edward M. Rubin
18. Gene TherapyGene Therapy with Vascular Endothelial Growth Factor, Jeffrey M. Isner
19. Vascular Disease and the Prospect of Gene Therapy, Heiko E. von der Leyen and Victor J. Dzau


0824798090 (hardcover : alk. paper)

96049906


Vascular endothelium--Pathophysiology.
Vascular endothelium--Physiology.
Endothelium.
Endothelins.
Thromboxanes.
Prostacyclin.
Heart Diseases--therapy.
Heart Diseases--physiopathology.
Endothelium--physiology.

QS 532.5 E7 ES6 1997 / E7 ES6 1997