Genes IV /

Lewin, Benjamin.

Genes IV / Benjamin Lewin. - Oxford ; New York : Oxford University Press, 1990. - xxii, 857 p. : ill. (some col.) ; 29 cm.

Includes bibliographical references.

Content
INTRODUCTION: Cells as Macromolecular Assemblies


1. Cells Obey the Laws of Physics and Chemistry


2. Cells are Organized into Compartments


PART I: DNA as a Store of Information


3. Genes are Mutable Units


4. DNA is the Genetic Material


5. The Topology of Nucleic Acids


6. Isolating the Gene


PART II: Translation--Expressing Genes as Proteins


7. The Assembly Line for Protein Synthesis


8. Transfer RNA: The Translational Adaptor


9. The Ribosome Translation Factory


10. The Messenger RNA Template


11. The Apparatus for Protein Localization


PART III: Transcription--Control of Prokaryotic Genes


12. Control at Initiation: RNA Polymerase-Promoter Interactions


13. A Panoply of Operons: The Lactose Paradigm and Others


14. Post-Transcriptional Feedback and Control


15. Control at Termination: Attenuation and Antitermination


16. Lytic Cascades and Lysogenic Repression


PART IV: Perpetuation of DNA


17. The Replicon: Unit of Replication


18. The Apparatus for DNA Replication


19. Systems that Safeguard DNA


PART V: The Packaging of DNA


20. About Genomes and Chromosomes


21. Organization of Nucleosomes in Chromatin


22. The Nature of Active Chromatin


PART VI: Constitution of the Eukaryotic Genome


23. The Extraordinary Power of DNA Technology


24. A Continuum of Sequences Includes Structural Genes


25. The Organization of Interrupted Genes


26. Structural Genes Evolve in Families


27. Genomes Sequestered in Organelles


28. Organization of Simple Sequence DNA


PART VII: Eukaryotic Transcription and RNA Processing


29. Building the Transcription Complex


30. Mechanisms of RNA Splicing


31. Control of RNA Processing


PART VIII: The Dynamic Genome--DNA in Flux


32. Recombination and Other Topological Manipulations of DNA


33. Transposons that Mobilize via DNA


34. Retroviruses and Retroposons


35. Engineering Changes in the Genome


PART IX: Genes in Development


36. Generation of Immune Diversity Involves Reorganization of the Genome


37. Regulation by Gene Rearrangement


38. Gene Regulation in Development: Gradients and Cascades


39. Oncogenes: Gene Expression and Cancer


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89016310


Genetics.

QU 450 L672g 1990