Platelets : a practical approach /

Platelets : a practical approach / edited by Steve P. Watson and Kalwant S. Authi. - Oxford ; New York : IRL Press at Oxford University Press, c1996. - xxvi, 370 p. : ill. ; 24 cm. - The Practical approach series ; 167 . - Practical approach series ; 167. .

Includes bibliographical references and index.

Contents
1. Platelet preparation and functional responses ;
2. Cellular model systems to study megakaryocyte differentiation ;
3. Techniques in the preparation of semi-permeable platelets and their uses ;
4. Use of fluorescent indicators to measure intracellular Ca2+ and other ions ;
5. Preparation of highly purified human platelet plasma and intracellular membranes using high voltage free flow electrophoresis and methods to study Ca2+ regulation ;
6. The use of flow-cytometry to study platelet activation ;
7. Identification, isolation, and characterization of platelet glycoproteins mediating platelet adhesion ;
8. Monoclonal antibodies to platelet cell surface antigens and their use ;
9. Measurement of protein phosphorylation, kinase activity, and G protein function in intact platelets and membrane preparations ;
10. Tyrosine phosphorylation ;
11. Study of proteins associated with the platelet cytoskeleton ;
12. Methods for measuring agonist-induced phosphlipid metabolism in intact human platelets ;
13. Cyclic nucleotides: measurement and function ;
14. Immunocytochemical and electron microscope studies of platelets ;
15. Clinical aspects of platelet function ;
16. Platelet procoagulent activity and its measurement ;
17. The study of platelet function in other species


0199635374 (pbk.) 0199635382 (hbk.)

95046193


Blood platelets--Research--Methodology.
Blood Platelets--physiology.
Signal Transduction--physiology.
Platelet Function Tests.

WH 300 P716 1996 / P716 1996