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Non-viral vectors for gene therapy / Nonviral vectors for gene therapy edited by Leaf Huang, Mien-chie Hung, Ernst Wagner. - 2nd edition : part II - Amsterdam ; Boston : Elsevier Academic Press, c2005. - 2 v. : ill. (some col.) ; 24 cm. - Advances in genetics ; v. 53-54 .

Includes bibliographical references and indexes.

Contents

1.Naked DNA, oligonucleotide and physical methods
1.The mechanism of naked DNA uptake and expression
2.Targeted delivery of therapeutic oligonucleotides to pulmonary circulation
3. Naked DNA for liver gene transfer
4.Hydrodynamic delivery
5.Electric pulse-mediated gene delivery to various animal tissues

2.Gene regulation
6.In vivo application of RNA interference: from functional genomics to therapeutics
7.A novel gene expression system: non-viral gene transfer for hemophilia as model systems
8.Site-specific integration with C31 integrase for prolonged expression of therapeutic genes
9.Sleeping beauty transposon-mediated gene therapy for prolonged expression;

3.Animal model and clinical study
10.Cancer-specific gene therapy
11.DNA vaccine
12.Airway gene therapy
13.Non-viral vector as vaccine carrier
14.Non-viral vectors for gene therapy: clinical trials in cardiovascular disease.

ISBN: 0120176548 (pt. 2) 9780120176540

Subjects--Topical Terms:
Genetic vectors.
Genetic transformation.
Gene therary.
Genetic Vectors--therapeutic use.
Gene Therapy--methods.
Gene Transfer Techniques.
Transformation, Genetic.

Dewey Class. No.: QU 560 N812 2005