Towards prolongation of the healthy life span : practical approaches to intervention /

Towards prolongation of the healthy life span : practical approaches to intervention / edited by Denham Harman, Robin Holliday, and Mohsen Meydani. - New York, N.Y. : New York Academy of Sciences, 1998. - xiv, 524 p. : ill. ; 24 cm. - Annals of the New York Academy of Sciences ; v. 854 .

Includes bibliographical references and index.

Contents

Aging: Phenomena and Theories / Denham Harman

Part I. Molecular and Cellular Changes with Age
Genes Involved in the Control of Cellular Proliferative Potential / Roger R. Reddel
Somatic Mutation and Aging / Alec Morley
Chromosomal Damage Rate, Aging, and Diet / Michael Fenech
Pluripotent Protective Effects of Carnosine, a Naturally Occurring Dipeptide / A.R. Hipkiss, J.E. Preston, D.T.M. Himsworth, V.C. Worthington, M. Keown, J. Michaelis, J. Lawrence, A. Mateen, L. Allende, P.A.M. Eagles, N. Joan Abbott
The Nature of Gerontogenes and Vitagenes: Antiaging Effects of Repeated Heat Shock on Human Fibroblasts / Suresh I.S. Rattan
Causes of Aging / Robin Holliday

Part II. Exercise and Aging
Intrinsic and Extrinsic Factors in Muscle Aging / Joseph G. Cannon
Age-associated Changes in the Response of Skeletal Muscle Cells to Exercise and Regeneration / Miranda D. Grounds
Age-associated Changes in the Innervation of Muscle Fibers and Changes in the Mechanical Properties of Motor Units / Anthony R. Luff
Oxidative Stress and Aging: Role of Exercise and Its Influences on Antioxidant Systems / Li Li Ji, Chris Leeuwenburgh, Steve Leichtweis, Mitch Gore, Russel Fiebig, John Hollander, Jeffery Bejma

Part III. Role of Mitochondria in Aging
Mitochondrial Aging: Open Questions / Kenneth B. Beckman, Bruce N. Ames
Mitochondrial DNA Mutations and Age / Takayuki Ozawa.

Part IV. Pharmacological intervention in aging processes: focus on oxyradicals and molecular mechanisms
Part V. Nutritional intervention in aging
Part VI. Antioxidants and aging
Part VII. Poster papers


1573311081 (cloth : alk. paper) 157331109X (pbk. : alk. paper)


Longevity--Congresses.
Aging--Molecular aspects--Congresses.
Aging--Physiological aspects--Congresses.

WT 116 T737 1998