000			01837cam a2200289 a 4500
999			_c7405 _d7405
001			579643
003			OSt
005			20211110060744.0
008			900625s1990 enka b 001 0 eng
010			_a 90007728
020			_a0199631948 _c$9.95
040			_aBUL _cBUL _dBUL _bENG _eRDA
082	0	0	_a660.63 _222 _bMOO
100	1		_aMoody, Peter C. E.
245	1	0	_aProtein engineering / _cPeter C.E. Moody and Anthony J. Wilkinson.
260			_aOxford ; _aNew York : _bIRL Press at Oxford University Press, _cc1990.
300			_ax, 85 p. : _bill. (some col.) ; _c23 cm.
490	1		_aIn focus
500			_a1. Introduction Historical perspective Protein evolution Protein engineering 2. Protein Structure Introduction Amino acids and proteins Protein structural organization Examination of protein structure Further reading 3. Preparation and Analysis of Mutant Proteins Expression systems Recombination DNA methods Site- directed mutagenesis Analysis of mutant proteins 4. Protein Engineering: Understanding Structure Tyrosyl-tRNA synthetase The serine proteneases Chloramphenicol acetyl transferase Rpressor proteins Conclsusion 5. Engineering Proteins: Practical Applications Engineering faster acting insulin Antibodies Enhancing activity in tyrosyl-rRNA synnthhetase Subtilisin: practical applications Engineering thermostabiltiy in lysozyme
504			_aIncludes Index. p83 -85
650		0	_aProtein engineering.
700	1		_aWilkinson, Tony.
830		0	_aIn focus (Oxford, England)
856	4	2	_3Publisher description _uhttp://www.loc.gov/catdir/enhancements/fy0635/90007728-d.html
856	4	1	_3Table of contents only _uhttp://www.loc.gov/catdir/enhancements/fy0635/90007728-t.html
942			_2ddc _cBO _h660.63 _i1 _kMOO _m660.63 MOO