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| 001 | 2471270 | ||
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| 005 | 20210722064554.0 | ||
| 008 | 900705s1991 maua b 001 0 eng | ||
| 010 | _a 90043581 | ||
| 020 | _a0878934529 | ||
| 040 |
_aBUL _cBUL _dBUL _beng _erda |
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| 082 | 0 | 0 |
_a575.1 _220 _bLI |
| 100 | 1 | _aLi, Wen-Hsiung | |
| 245 | 1 | 0 |
_aFundamentals of molecular evolution / _cWen-Hsiung Li & Dan Graur. |
| 260 |
_aSunderland, Mass. : _bSinauer Associates, _cc1991. |
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| 300 |
_axv, 284 p. : _bill. ; _c24 cm. |
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| 500 | _aContents; Introduction: What is molecular evolution? 1. Gene structure and mutation DNA sequences Gene structure Genetic codes Mutation 2. Dynamics of genes in populations Changes in allele frequencies Natural selection Random genetic drift Effective population size etc. 3. Evolutionary change in nucleotide sequences Nucleotide substitution in a DNA sequence Number of nucleotide substitutions between two DNA sequences Alignment of nucleotide and amino acid sequences Indirect estimation of the number of nucleotide substitutions 4. Rates and patterns of nucleotide substitution Rates of nucleotide substitution Causes of variation in substitution rates A case of positive selection: Lysozyme in cows and langurs Molecular clocks etc. 5. Molecular phylogeny Impact of molecular data on phylogenetic studies Phylogenetic trees Methods of tree reconstruction Phenetics versus cladistics Estimation of branch lengths etc. 6. Evolution by gene duplication and exon shuffling Types of DNA duplication Domains and exons Domain duplication and gene elongation Formation of gene families and the acquisition of new functions etc 7. Evolution by transposition Transposition and retroposition Transposable elements Retrosequences Effects of transposition on the host genome Hybrid dysgenesis Transposition and speciation etc. 8. Genome organization and evolution C values Evolution of genome size in bacteria Genome size of eukaryotes and the C-value paradox The repetitive structure of the eukaryotic genome Mechanisms for increasing genome size etc. | ||
| 504 | _aIncludes bibliographical references and index. | ||
| 650 | 0 | _aMolecular evolution. | |
| 700 | 1 | _aGraur, Dan | |
| 942 |
_2ddc _cBOOK-CA _h575.1 _i1 _kLI _m575.1 LI |
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