000			02082cam a22003617a 4500
001			17108844
003			OSt
005			20240513092916.0
008			120106s2011 enka b 001 0 eng d
010			_a 2011499897
020			_a9781853159473
020			_a1853159476
035			_a(OCoLC)ocn754842945
040			_aBUL _cBUL _dBUL _beng _erda
042			_alccopycat
082	0	0	_a610 _223 _bRAW
100	1		_aRawlins, Michael D. _q(Michael David)
245	1	0	_aTherapeutics, evidence and decision-making / _cMichael D. Rawlins ; foreword by Parveen J. Kumar.
260			_aLondon : _bHodder Arnold, _cc2011.
300			_axiii, 230 p. : _bill. ; _c24 cm.
500			_aContents; Section 1: Introduction 1.1 The nature of evidence 1.2 Probability 1.3 Clinical endpoints of benefits and harms 1.4 Statistical expressions of benefit and harm 1.5 Bias and confounding etc. Section 2: Randomized controlled trials 2.1 General principles 2.2 Stopping rules 2.3 Analysis of subgroups 2.4 Safety 2.5 Generalizability Section 3: Observational studies 3.1 General overview 3.2 Historical controlled trials 3.3 Concurrent cohort studies 3.4 Case - control designs 3.5 Databases etc. Section 4: Qualitative research 4.1 Approaches and methods 4.2 Uses in the evaluation of therapeutic interventions Section 5: Economic evaluation 5.1 General principles 5.2 Cost effectiveness, cost - utility and cost - minimization analyses 5.3 Cost - consequences analysis Section 6: Decision-making 6.1 For individuals 6.2 For populations
504			_aIncludes bibliographical references and index.
650		0	_aEvidence-based medicine.
650		0	_aClinical medicine _xDecision making.
650		0	_aTherapeutics.
650	1	2	_aEvidence-Based Medicine
650	2	2	_aDecision Making.
650	2	2	_aDiagnostic Techniques and Procedures.
700			_aKumar, Parveen J.
710	2		_aRoyal Society of Medicine (Great Britain)
942			_2ddc _cBO _h610 _i1 _kRAW _m610 RAW
999			_c4782 _d4782