Mandell, Douglas, and Bennett's principles and practice of infectious diseases / [edited by] John E. Bennett, . . . [et al]

Includes bibliographical references and index.

Table of content
Part I Basic Principles in the Diagnosis and Management of Infectious Diseases Section A. Microbial Pathogenesis 1 A Molecular Perspective of Microbial Pathogenicity 2 Microbial Adherence 3 Toxins Section B. Host Defense Mechanisms 4 Innate (General or Nonspecific) Host Defense Mechanisms 5 Human Genetics and Infection 6 Antibodies 7 Complement 8 Granulocytic Phagocytes 9 Cell-Mediated Defense Against Infection 10 Nutrition, Immunity, and Infection 11 Probiotics 12 Evaluation of the Patient with Suspected Immunodeficiency Section C. Epidemiology of Infectious Diseases 13 Epidemiologic Principles 14 Outbreak Investigation 15 Emerging and Reemerging Infectious Disease Threats 16 Hospital Preparedness for Emerging and Highly Contagious Infectious Diseases Section D. Clinical Microbiology 17 The Clinician and the Microbiology Laboratory Section E. Anti-Infective Therapy 18 Principles of Anti-infective Therapy 19 Molecular Mechanisms of Antibiotic Resistance in Bacteria 20 Pharmacokinetics and Pharmacodynamics of Anti-infective Agents 21 Penicillins 22 Cephalosporins 23 Other -Lactam Antibiotics 24 -Lactam Allergy 25 Fusidic Acid 26 Aminoglycosides 27 Tetracyclines and Chloramphenicol 28 Rifamycins 29 Metronidazole 30 Macrolides, Clindamycin, and Ketolides 31 Glycopeptides, Streptogramins, and Lipopeptides 32 Polymyxins (Polymyxin B and Colistin) 33 Oxazolidinones 34 Sulfonamides and Trimethoprim 35 Quinolones 36 Unique Antibacterial Agents 37 Urinary Tract Agents: Nitrofurantoin and Methenamine 38 Topical Antibacterials 39 Antimycobacterial Agents 40 Antifungal Agents 41 Antiviral Drugs (Other Than Antiretrovirals) 42 Immunomodulators 43 Hyperbaric Oxygen 44 Agents Active against Parasites and Pneumocystis 45 Complementary and Alternative Medicines for Infectious Diseases 46 Antimicrobial Management: Cost and Resistance 47 Interpretation of Clinical Trials of Antimicrobial Agents 48 Outpatient Parenteral Antimicrobial Therapy 49 Tables of Antimicrobial Agent Pharmacology Part II Major Clinical Syndromes Section A. Fever 50 Temperature Regulation and the Pathogenesis of Fever 51 Fever of Unknown Origin 52 The Acutely Ill Patient with Fever and Rash Section B. Upper Respiratory Tract Infections 53 The Common Cold 54 Pharyngitis 55 Actue Laryngitis 56 Acute Laryngotracheobronchitis (Croup) 57 Otitis Externa, Otitis Media, and Mastoiditis 58 Sinusitis 59 Epiglottitis 60 Infections of the Oral Cavity, Neck, and Head Section C. Pleuropulmonary and Bronchial Infections 61 Acute Bronchitis 62 COPD, Chronic Bronchitis, and Acute Exacerbations 63 Bronchiolitis 64 Acute Pneumonia 65 Empyema and Pleural Effusion 66 Lung Abscess 67 Chronic Pneumonia 68 Cystic Fibrosis Section D. Urinary Tract Infections 69 Urinary Tract Infections Section E. Sepsis 70 Sepsis, Severe Sepsis, and Septic Shock Section F. Intra-abdominal Infection 71 Peritonitis and Intraperitoneal Abscesses 72 Infections of the Liver and Biliary System 73 Pancreatic Infections 74 Splenic Abscess 75 Appendicitis 76 Diverticulitis and Typhlitis Section G. Cardiovascular Infections 77 Endocarditis and Intravascular Infections 78 Prosthetic Valve Endocarditis 79 Infections of Non-Valvular Cardiovascular Devices 80 Prophylaxis of Infective Endocarditis 81 Myocarditis and Pericarditis 82 Mediastinitis Section H. Central Nervous System Infections 83 Approach to the Patient with Central Nervous System Infection 84 Acute Meningitis 85 Infections of CSF Shunts 86 Chronic Meningitis 87 Encephalitis, Myelitis, and Neuritis 88 Brain Abscess 89 Subdural Empyema, Epidural Abscess, and Intracranial Suppurative Thrombophlebitis Section I. Skin and Soft Tissue Infections 90 Cellulitis, Necrotizing Fasciitis and Subcutaneous Tissue Infections 91 Myositis 92 Lymphadenitis and Lymphangitis Section J. Gastrointestinal Infections and Food Poisoning 93 Principles and Syndromes of Enteric Infection 94 Esophagitis 95 Nausea, Vomiting, and Noninflammatory Diarrhea 96 Antibiotic-Associated Colitis 97 Inflammatory Enteritides 98 Enteric Fever and Other Causes of Abdominal Symptoms with Fever 99 Foodborne Disease 100 Tropical Sprue/Enteropathy 101 Whipple's Disease Section K. Bone and Joint Infections 102 Infectious Arthritis 103 Osteomyelitis 104 Infections in Prostheses in Bones and Joints Secction L. Diseases of the Reproductive Organs and Sexually Transmitted Diseases 105 Genital Skin and Mucous Membrane Lesions 106 Urethritis 107 Vulvovaginitis and Cervicitis 108 Infections of the Female Pelvis 109 Prostatitis, Epididymitis, and Orchitis Section M. Eye Infections 110 Microbial Conjunctivitis 111 Microbial Keratitis 112 Endophthalmitis 113 Infectious Causes of Uveitis 114 Periocular Infections Section N. Hepatitis 115 Acutel Hepatitis 116 Chronic Viral Hepatitis Section O. Acquired Immunodeficiency Syndrome 117 Global Perspectives on HIV Infection and Acquired Immunodeficiency Syndrome 118 Epidemiology and Prevention of AIDS and HIV Infection 119 Diagnosis of Human Immunodeficiency Virus Infection 120 The Immunology of Human Immunodeficiency Virus Infection 121 General Clinical Manifestations of Human Immunodeficiency Virus Infection 122 Pulmonary Manifestations of Human Immunodeficiency Virus Infection 123 GI and Hepatobiliary Manifestations of Human Immunodeficiency Virus Infection 124 Neurologic Diseases Caused by HIV-1 and Opportunistic Infections 125 Malignancies in Human Immunodeficiency Virus Infection 126 Human Immunodeficiency Virus Infection in Women 127 Pediatric Human Immunodeficiency Virus Infection 128 Antiretroviral Therapy for Human Immunodeficiency Virus Infection 129 Management of Opportunistic Infections Associated with HIV Infection 130 Vaccines for Human Immunodeficiency Virus-1 Infection Section P. Miscellaneous Syndromes 131 Chronic Fatigue Syndrome Part III Infectious Diseases and Their Etiologic Agents Section A. Viral Diseases 132 Introduction to Viruses and Viral Diseases - DNA Viruses - Poxviridae 133 Orthopoxviruses: Vaccinia, Variola, Monkeypox, and Cowpox 134 Other Poxviruses: Parapoxviruses, Molluscum Contagiosum, and Tanapox Herpesviridae 135 Introduction to Herpesviridae 136 Herpes Simplex Virus 137 Varicella-Zoster Virus 138 Cytomegalovirus 139 Epstein-Barr Virus (Infectious Mononucleosis) 140 Human Herpesvirus Types 6 and 7 141 Kaposi's Sarcoma-Associated Herpesvirus (Human Herpesvirus Type 8) 142 Herpes B Virus - Adenoviridae 143 Adenovirus - Papovaviridae 144 Papillomaviruses 145 JC, BK, and Other Polyomaviruses; Progressive Multifocal Leukoencephalopathy - Hepadnaviridae 146 Hepatitis B Virus and Hepatitis Delta Virus - Parvoviridae 147 Human Parvoviruses - RNA Viruses - Reoviridae 148 Orthoreoviruses and Orbiviruses 149 Coltiviruses and Seadornaviruses (Colorado Tick Fever) 150 Rotaviruses - Togaviridae 151 Alphaviruses 152 Rubella Virus (German Measles) - Flaviviruses 153 Flaviviruses (Yellow Fever, Dengue, Dengue Hemorrhagic Fever, Japanese Encephalitis, West Nile Encephalitis, St. Louis Encephalitis, Tick-Borne Encephalitis) 154 Hepatitis C - Coronaviridae 155 Coronaviruses, Including SARS-Associated Coronavirus Paramyxoviridae 156 Parainfluenza Viruses 157 Mumps Virus 158 Respiratory Syncytial Virus 159 Human Metapneumovirus 160 Measles Virus (Rubeola) 161 Zoonotic Paramyxoviruses: Hendra, Nipah, and Menangle Viruses Rhabdoviridae 162 Vesicular Stomatitis Virus and Related Viruses 163 Rhabdoviruses - Filoviridae 164 Marburg and Ebola Virus Hemorrhagic Fevers - Orthomyxoviridae 165 Influenza Viruses Including Avian Influenza - Bunyaviridae 166 California Encephalitis, Hantavirus Pulmonary Syndrome, and Bunyavirid Hemorrhagic Fevers - Arenaviridae 167 Lymphocytic Choriomeningitis Virus, Lassa Virus, and the South American Hemorrhagic Fevers - Retroviridae 168 Human T-Cell Lymphotropic Virus Types I and II 169 Human Immunodeficiency Viruses - Picornaviridae 170 Introduction to the Enteroviruses 171 Poliovirus 172 Coxsackieviruses, Echoviruses, and Newer Enteroviruses 173 Hepatitis A Virus - Caliciviridae and Other Gastrointestinal Viruses 174 Rhinovirus 175 Noroviruses and Other Caliciviruses 176 Astroviruses and Picobirnaviruses - Unclassified Viruses 177 Hepatitis E Virus Section B. Prion Diseases 178 Prions and Prion Diseases of the Central Nervous System (Transmissible Neurodegenerative Diseases) Section C. Chlamydial Diseases 179 Introduction to Chlamydial Diseases 180 Chlamydia trachomatis (Trachoma, Perinatal Infections, Lymphogranuloma Venereum, and Other Genital Infections) 181 Chlamydophila (Chlamydia) psittaci (Psittacosis) 182 Chlamydophila (Chlamydia) pneumoniae 183 Introduction to Mycoplasma Diseases 184 Mycoplasma pneumoniae and Atypical Pneumonia Section D. Mycoplasma Diseases 185 Genital Mycoplasmas: Mycoplasma genitalium, Mycoplasma hominis, and Ureaplasma Species Section E. Rickettsioses, Ehrlichioses, and Anaplasmosis 186 Introduction to Rickettsioses, Ehrlichioses and Anaplasmosis 187 Rickettsia rickettsii and Other Spotted Fever Group Rickettsiae (Rocky Mountain Spotted Fever and Other Spotted Fevers) 188 Rickettsia akari (Rickettsialpox) 189 Coxiella burnetii (Q Fever) 190 Rickettsia prowazekii (Epidemic or Louse-Borne Typhus) 191 Rickettsia typhi (Murine Typhus) 192 Orientia Tsutsugamushi 193 Ehrlichia Chaffeensis and Ehrlichia Phagocytophila Section F. Bacterial Diseases 194 Introduction to Bacteria and Bacterial Diseases - Gram-Positive Cocci 195 Staphylococcus aureus (Including Staphylococcal Toxic Shock) 196 Staphylococcus epidermidis and Other Coagulase-Negative Staphylococci 197 Classification of Streptococci 198 Streptococcus pyogenes 199 Nonsuppurative Poststreptococcal Sequelae: Rheumatic Fever and Glomerulonephritis 200 Streptococcus pneumoniae 201 Enterococcus Species, Streptococcus bovis, and Leuconostoc Species 202 Streptococcus agalactiae (Group B Streptococcus) 203 Viridans Streptococci, Groups C and G Streptococci, and Gemella morbillorum 204 Streptococcus anginosus Group - Gram-Positive Bacilli 205 Corynebacterium diphtheriae 206 Corynebacteria other than Diphtheria and Rhodococcus 207 Listeria monocytogenes 208 Bacillus anthracis (Anthrax) 209 Bacillus Species and Other than Bacillus anthracis 210 Erysipelothrix rhusiopathiae - Gram-Negative Cocci 211 Neisseria meningitidis 212 Neisseria gonorrhoeae 213 Moraxella catarrhalis and Other Gram-Negative Cocci - Gram-Negative Bacilli 214 Vibrio cholerae 215 Other Pathogenic Vibrios 216 Campylobacter jejuni and Related Species 217 Helicobacter pylori and Other Gastric Helicobacter Species 218 Enterobacteriaceae 219 Pseudomonas species, including Ps. aeruginosa 220 Stenotrophomonas maltophilia and Burkholderia cepacia complex 221 Burkholderia pseudomallei and Burkholderia mallei 222 Acinetobacter Species 223 Salmonella Species, Including Salmonella typhi 224 Shigella Species (Bacillary Dysentery) 225 Haemophilus species (incluing H. influenzae and chancroid) 226 Brucella Species 227 Francisella tularensis (Tularemia) 228 Pasteurella Species 229 Yersinia Species, Including Plague 230 Bordetella Pertussis 231 Rat-Bite Fever Streptobacillus moniliformis and Spirillum minus 232 Legionella 233 Other Legionella Species 234 Capnocytophaga 235 Bartonella, Including Cat-Scratch Disease 236 Calymmatobacterium granulomatis (Donovanosis, Granuloma Inguinale) 237 Other Gram-Negative and Gram-Variable Bacilli - Spirochetes 238 Treponema pallidum (Syphilis) 239 Endemic Treponematoses 240 Leptospira Species (leptospirosis) 241 Borrelia Species (Relapsing Fever) 242 Borrelia burgdorferi (Lyme Disease, Lyme Borreliosis) - Anaerobic Bacteria 243 Anaerobic Infections: General Concepts 244 Clostridium tetani (Tetanus) 245 Clostridium botulinum (Botulism) 246 Gas Gangrene and Other Clostridium-Associated Diseases 247 Bacteroides, Prevotella, Porphyromonas, and Fusobacterium Species 248 Anaerobic Cocci; Anaerobic 249 Anaerobic Gram-Positive Non-sporulating Bacilli - Mycobacterial Diseases 250 Mycobacterium tuberculosis 251 Mycobacterium leprae 252 Mycobacterium Avium-intracellulare 253 Infections due to Mycobacteria other than M. tuberculosis and M. Avium Complex -Higher Bacterial Diseases 254 Nocardia Species 255 Agents of Actinomycosis Section G. Mycoses 256 Introduction to Mycoses 257 Candida Species 258 Aspergillus Species 259 Agents of Mucormycosis 260 Sporothrix schenckii 261 Agents of Chromomycosis 262 Agents of Mycetoma 263 Cryptococcus neoformans 264 Histoplasma capsulatum 265 Blastomyces dermatitidis 266 Coccidioides Species 267 Dermatophytosis and Other Superficial Mycoses 268 Paracoccidioides brasiliensis 269 Uncommon Fungi and Prototheca 270 Pneumocystis 271 Microsporidiosis Section H. Protozoal Diseases 272 Introduction to Protozoal Diseases 273 Entamoeba species including amoebiasis 274 Free-Living Amebas 275 Plasmodium Species (Malaria) 276 Leishmania Species: Visceral, Cutaneous, and Mucocutaneous Leishmaniasis 277 Biology of Trypanosoma Species 278 Agents of African Trypanosomiasis (Sleeping Sickness) 279 Toxoplasma gondii 280 Giardia lamblia 281 Trichomonas vaginalis 282 Babesia Species 283 Cryptosporidium Species 284 Isospora belli, Sarcocystis Species, Blastocystis hominis and Cyclospora Section I. Diseases Due to Toxic Algae 285 Human Illness Associated with Harmful Algal Blooms Section J. Diseases Due to Helminths 286 Introduction to Helminth Infections 287 Intestinal Nematodes (Roundworms) 288 Tissue Nematodes, Including Trichinosis, Dracunculiasis, and the Filariases 289 Trematodes (Schistosomes and Other Flukes) 290 Cestodes (Tapeworms) 291 Visceral Larva Migrans and Other Unusual Helminth Infections Section K. Ectoparasitic Diseases 292 Introduction to Ectoparasitic Diseases 293 Lice (Pediculosis) 294 Scabies 295 Myiasis and Tungiasis 296 Mites (Including Chiggers) 297 Ticks (Including Tick Paralysis) Section L. Diseases of Unknown Etiology 298 Kawasaki Syndrome Part IV Special Problems Section A. Nosocominal Infections 299 Organization for Infection Control 300 Isolation 301 Disinfection, Sterilization, and Control of Hospital Waste 302 Infections Caused by Percutaneous Intravascular Devices 303 Nosocomial Pneumonia 304 Nosocomial Urinary Tract Infections 305 Nosocomial Hepatitis and Other Infections Transmitted by Blood and Blood Products 306 Human Immunodeficiency Virus in Health Care Settings 307 Nosocomial Herpesvirus Infections Section B. Infections in Special Hosts 308 Infections in the Immunocompromised Host: General Principles 309 Prophylaxis and Empirical Therapy of Infection in Cancer Patients 310 Risk Factors and Approaches to Infections in Transplant Recipients 311 Infections in Hematopoietic Stem Cell Transplant Recipients 312 Infections in Solid Organ Transplant Recipients 313 Infections in Patients with Spinal Cord Injury 314 Infections in the Elderly 315 Infections in Asplenic Patients 316 Infections in Injection Drug Users 317 Postoperative Infections and Antimicrobial Prophylaxis Section C. Surgical and Trauma-Related Infections 318 Infections in Patients with Burns 319 Bites Section D. Immunization 320 Immunization Section E. Biodefense 321 Bioterrorism: An Overview 322 Plague as Bioterrorism Weapon 323 Tularemia as a Bioterrorism Weapon 324 Smallpox as an Agent of Bioterrorism 325 Anthrax as an Agent of Bioterrorism 326 Botulinum Toxin as an Agent of Bioterrorism 327 Viral Hemorrhagic Fevers as Agents of Bioterrorism Section F. Zoonoses 328 Zoonoses Section G. Protection of Travelers 329 Protection of Travelers 330 Infections in Returning Travelers