TY - BOOK AU - Huang,Leaf AU - Hung,Mien-chie AU - Wagner,Ernst TI - Non-viral vectors for gene therapy SN - 012017653X (pt. 1) U1 - QU 560 N812 2005 PY - 2005/// CY - Amsterdam, Boston PB - Elsevier Academic Press KW - Genetic vectors KW - Genetic transformation KW - Gene therary KW - Genetic Vectors KW - therapeutic use KW - Gene Therapy KW - methods KW - Gene Transfer Techniques KW - Transformation, Genetic N1 - Includes bibliographical references and indexes; Contents 1. Basic concepts 1.Recent Advances in Non-viral Gene Delivery 2.Barriers to gene delivery using synthetic vectors 3.Pharmacokinetics of Plasmid DNA-Based Nonviral Gene Medicine 2.Cationic Liposomes 4.What Role can chemistry play in cationic liposome-based gene therapy research today? 5.Lipoplex structures and their distinct cellular pathways 6. Diffusible-PEG-Lipid stabilized plasmid lipid particles 7.Toxicity of Catonic lipid-DNA complexes 3. Cationic Polymers 8.Polyethylenimine (PEI) 9.Pluronic Block Copolymers for gene delivery 10.Terplex gene delivery system 11.Design of polyphosphoester-DNA nanoparticles for nonviral gene delivery 12.Development of HVJ envelope vector and its application to gene therapy 13.Targeting of polyplexes: towards synthetic virus vector systems UR - http://www.loc.gov/catdir/enhancements/fy0626/2005279973-d.html UR - http://www.loc.gov/catdir/enhancements/fy0626/2005279973-t.html ER -