Non-viral vectors for gene therapy /
Nonviral vectors for gene therapy
edited by Leaf Huang, Mien-chie Hung, Ernst Wagner.
- 2nd edition : part I
- Amsterdam ; Boston : Elsevier Academic Press, c2005.
- 2 v. : ill. (some col.) ; 24 cm.
- Advances in genetics ; v. 53-54 .
Includes bibliographical references and indexes.
Contents
1. Basic concepts 1.Recent Advances in Non-viral Gene Delivery 2.Barriers to gene delivery using synthetic vectors 3.Pharmacokinetics of Plasmid DNA-Based Nonviral Gene Medicine
2.Cationic Liposomes 4.What Role can chemistry play in cationic liposome-based gene therapy research today? 5.Lipoplex structures and their distinct cellular pathways 6. Diffusible-PEG-Lipid stabilized plasmid lipid particles 7.Toxicity of Catonic lipid-DNA complexes
3. Cationic Polymers 8.Polyethylenimine (PEI) 9.Pluronic Block Copolymers for gene delivery 10.Terplex gene delivery system 11.Design of polyphosphoester-DNA nanoparticles for nonviral gene delivery 12.Development of HVJ envelope vector and its application to gene therapy 13.Targeting of polyplexes: towards synthetic virus vector systems.