TY - BOOK AU - Huang,Leaf AU - Hung,Mien-chie AU - Wagner,Ernst TI - Non-viral vectors for gene therapy SN - 0120176548 (pt. 2) U1 - QU 560 N812 2005 PY - 2005/// CY - Amsterdam, Boston PB - Elsevier Academic Press KW - Genetic vectors KW - Genetic transformation KW - Gene therary KW - Genetic Vectors KW - therapeutic use KW - Gene Therapy KW - methods KW - Gene Transfer Techniques KW - Transformation, Genetic N1 - Includes bibliographical references and indexes; Contents 1.Naked DNA, oligonucleotide and physical methods 1.The mechanism of naked DNA uptake and expression 2.Targeted delivery of therapeutic oligonucleotides to pulmonary circulation 3. Naked DNA for liver gene transfer 4.Hydrodynamic delivery 5.Electric pulse-mediated gene delivery to various animal tissues 2.Gene regulation 6.In vivo application of RNA interference: from functional genomics to therapeutics 7.A novel gene expression system: non-viral gene transfer for hemophilia as model systems 8.Site-specific integration with C31 integrase for prolonged expression of therapeutic genes 9.Sleeping beauty transposon-mediated gene therapy for prolonged expression; 3.Animal model and clinical study 10.Cancer-specific gene therapy 11.DNA vaccine 12.Airway gene therapy 13.Non-viral vector as vaccine carrier 14.Non-viral vectors for gene therapy: clinical trials in cardiovascular disease UR - http://www.loc.gov/catdir/enhancements/fy0626/2005279973-d.html ER -