Amyotrophic lateral sclerosis /
Hiroshi Mitsumoto, David A. Chad, Erik P. Pioro.
- Philadelphia : F.A. Davis, c1998.
- xxv, 480 p. : ill. ; 26 cm.
- Contemporary neurology series ; 49 .
Includes bibliographical references and index.
Contents
Part One: Introduction to ALS 1. History, Terminology, and Classification of ALS 2. Epidemiology 3. Functional Neuroanatomy of the Motor System
Part Two: Clinical Features of ALS 4. Clinical Features: Signs and Symptoms 5. Electrodiagnosis 6. The Differential Diagnosis of ALS 7. Diagnostic Investigation for ALS 8. Neuroimaging 9. Course and Prognosis 10. Familial ALS
Part Three: Pathology and Pathogenesis 11. Neuropathology 12. Excitotoxicity and Oxidative Damage in ALS pathogenesis 13. The Immune Hypothesis 14. Hypotheses for Viral and Other Transmissible Agents in ALS 15. Neurotrophic Factors for Motor Neurons 16. Other Hypotheses of ALS 17. Animal Models of ALS
Part Four: Treatment and Management 18. Comprehensive Care 19. Symptomatic Treatment 20. Treatment Trials 21. Physical Rehabilitation 22. Pulmonary Function and Respiratory Failure 23. Speech Therapy and Communication Management 24. Nutritional Management 25. Psychological Management 26. Medical Economics, Legality and Medical Ethics