Nonviral vectors for gene therapy /
edited by Leaf Huang, Mien-chie Hung, Ernst Wagner.
- San Diego, CA : Academic Press, c1999.
- xxv, 442 p. : ill. (some col.) ; 24 cm.
Includes bibliographical references and index.
Contents
Part I: Introduction Chapter 1: Introduction, L.Huang and E. Viroonhatapan.
Part II: Cationic Liposomes: Chapter 2: Progress in Gene Delivery Research and Development, P. Felgner. Chapter 3: Cationic Lipid-Mediated Gene Delivery to the Airways, J. Marshall, N. Yew, S. Eastman, C. Jiang, R. Scheule, S. Cheng. Chapter 4: Structure and Structure-Activity Relationship of Lipid-Based Gene Delivery Systems, D. Lasic. Chapter 5: Self-Assembled Structures of Lipid/DNA Nonviral Gene Delivery Systems from Synchorotron X-Ray Diffraction, C. Safinya, I. Koltover. Chapter 6: Sites of Uptake and Expression of Cationic Liposome/DNA Complexes Injected Intravenously, J. McLean, G. Thurston, D. McDonald.
Part III: Other Vectors: Chapter 7: Nuclear Transport of Exogenous DNA, M. Sebestye;n and J. Wolff. Chapter 8: Particle-Mediated Gene Delivery: Applications to Canine and Other Larger Animal Systems, N.-S. Yang, G. Hogge, E.G. MacEwen. Chapter 9: Polyethylenimines: A Family of Potent Polymers for Nucleic Acid Delivery, A. Kichler, J.-P. Behr, P. Erbacher. Chapter 10: Ligand-Polycation Conjugates for Receptor-Targeted Gene Transfer, E. Wagner. Chapter 11: The Perplexing Delivery Mechanism of Lipoplexes, L. Barron and F. Szoka, Jr.. Chapter 12: Biopolymer-DNA Nanospheres, K. Leong. Chapter 13: Novel Lipidic Vectors for Gene Transfer, S. Li, L. Huang.
Part IV: Animal Models and Clinical Trials: Chapter 14: Mechanisms of Cationic Liposome-Mediated Transfection of the Lung Endothelium, D. Liu, J. Knapp, Y. Song. Chapter 15: Cystic Fibrosis Gene Therapy, U. Griesenbach, D. Geddes, E. Alton. Chapter 16: Targeting HER-2/neu-Overexpressing Cancer Cells with Transcriptional Repressor Genes Delivered by Cationic Liposome, M.-C. Hung, S.-C. Wang, G. Hortobagyi. Chapter 17: Immune Pathways Used in Nucleic Acid Vaccination, G. Rhodes. Chapter 18: A Novel Gene Regulatory System, S. Chua, M. Burcin, Y. Wang, S. Tsai.
0123584655 9780123584656
Gene therapy. Genetic vectors. DNA-ligand interactions. Liposomes. Drug targeting.