TY - BOOK AU - Rawlins,Michael D. AU - Kumar, Parveen J. ED - Royal Society of Medicine (Great Britain) TI - Therapeutics, evidence and decision-making SN - 9781853159473 U1 - 610 23 PY - 2011/// CY - London PB - Hodder Arnold KW - Evidence-based medicine KW - Clinical medicine KW - Decision making KW - Therapeutics KW - Evidence-Based Medicine KW - Decision Making KW - Diagnostic Techniques and Procedures N1 - Contents; Section 1: Introduction 1.1 The nature of evidence 1.2 Probability 1.3 Clinical endpoints of benefits and harms 1.4 Statistical expressions of benefit and harm 1.5 Bias and confounding etc. Section 2: Randomized controlled trials 2.1 General principles 2.2 Stopping rules 2.3 Analysis of subgroups 2.4 Safety 2.5 Generalizability Section 3: Observational studies 3.1 General overview 3.2 Historical controlled trials 3.3 Concurrent cohort studies 3.4 Case - control designs 3.5 Databases etc. Section 4: Qualitative research 4.1 Approaches and methods 4.2 Uses in the evaluation of therapeutic interventions Section 5: Economic evaluation 5.1 General principles 5.2 Cost effectiveness, cost - utility and cost - minimization analyses 5.3 Cost - consequences analysis Section 6: Decision-making 6.1 For individuals 6.2 For populations ; Includes bibliographical references and index UR - http://www.loc.gov/catdir/enhancements/fy1214/2011499897-b.html UR - http://www.loc.gov/catdir/enhancements/fy1214/2011499897-d.html ER -