Understanding pathophysiology / 
Sue E. Huether, Kathryn L. McCance. 
 - 1st ed 
 - St. Louis, Mo. :  Elsevier,  c2017. 
 - xix, 1150p. :  ill. (chiefly col.) ;  28 cm.  
<br/><br/>Includes Index: 1119-1150 
<br/><br/>CONTENT<br/><br/>Part One Basic Concepts of Pathophysiology<br/>Unit 1 The Cell<br/><br/>1 Cellular Biology<br/>Prokaryotes and Eukaryotes<br/>Cellular Functions<br/>Structure and Function of Cellular Components<br/>Cell-to-Cell Adhesions<br/>Cellular Communication and Signal Transduction<br/>Cellular Metabolism<br/>Membrane Transport: Cellular Intake and Output<br/>Cellular Reproduction: The Cell Cycle<br/>Tissues<br/><br/><br/>2 Genes and Genetic Diseases<br/>DNA, RNA, and Proteins: Heredity at the Molecular Level<br/>Chromosomes<br/>Elements of Formal Genetics<br/>Transmission of Genetic Diseases<br/>Linkage Analysis and Gene Mapping<br/>Multifactorial Inheritance<br/><br/>3 Epigenetics and Disease<br/>Epigenetic Mechanisms<br/>Epigenetics and Human Development<br/>Genomic Imprinting<br/>Inheritance of Epigenetic States<br/>Epigenetics and Cancer<br/>Future Directions<br/><br/>4 Altered Cellular and Tissue Biology<br/>Cellular Adaptation<br/>Cellular Injury<br/>Manifestations of Cellular Injury: Accumulations<br/>Cellular Death<br/>Aging and Altered Cellular and Tissue Biology<br/>Somatic Death<br/><br/>5 Fluids and Electrolytes, Acids and Bases<br/>Distribution of Body Fluids and Electrolytes<br/>Alterations in Water Movement<br/>Sodium, Chloride, and Water Balance<br/>Alterations in Sodium, Chloride, and Water Balance<br/>Alterations in Potassium and Other Electrolytes<br/>Acid-Base Balance<br/>Pediatric Considerations<br/>Geriatric Considerations<br/><br/>Unit 2 Mechanisms of Self-Defence<br/>6 Innate Immunity<br/>Human Defence Mechanisms<br/>Acute and Chronic Inflammation<br/>Wound Healing<br/>Pediatric Considerations<br/>Geriatric Considerations<br/><br/>7 Adaptive Immunity<br/>Third Line of Defence: Adaptive Immunity<br/>Antigens and Immunogens<br/>Antibodies<br/>Immune Response: Collaboration of B Cells and T Cells<br/>Cell-Mediated Immunity<br/>Pediatric Considerations<br/>Geriatric Considerations<br/><br/>8 Infection and Defects in Mechanisms of Defence<br/>Infection<br/>Deficiencies in Immunity<br/>Hypersensitivity: Allergy, Autoimmunity, and Alloimmunity<br/><br/>9 Stress and Disease<br/>Historical Background and General Concepts<br/>The Stress Response<br/>Stress, Personality, Coping, and Illness<br/>Geriatric Considerations<br/><br/>Unit 3 Cellular Proliferation: Cancer<br/>10 Biology of Cancer<br/>Cancer Terminology and Characteristics<br/>The Biology of Cancer Cells<br/>Clinical Manifestations of Cancer<br/>Diagnosis, Characterization, and Treatment of Cancer<br/><br/>11 Cancer Epidemiology<br/>Genetics, Epigenetics, and Tissue<br/>Incidence and Mortality Trends<br/>In Utero and Early Life Conditions<br/>Environmental and Lifestyle Factors<br/><br/>12 Cancer in Children and Adolescents<br/>Incidence, Etiology, and Types of Childhood Cancer<br/>Prognosis<br/><br/>Part Two Body Systems and Diseases<br/>Unit 4 The Neurological System<br/><br/>13 Structure and Function of the Neurological System<br/>Overview and Organization of the Nervous System<br/>Cells of the Nervous System<br/>The Nerve Impulse<br/>The Central Nervous System<br/>The Peripheral Nervous System<br/>The Autonomic Nervous System<br/>Geriatric Considerations<br/><br/>14 Pain, Temperature, Sleep, and Sensory Function<br/>Pain<br/>Temperature Regulation<br/>Sleep<br/>The Special Senses<br/>Somatosensory Function<br/>Geriatric Considerations<br/>Geriatric Considerations<br/>Geriatric Considerations<br/><br/>15 Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function<br/>Alterations in Cognitive Systems<br/>Alterations in Cerebral Hemodynamics<br/>Alterations in Neuromotor Function<br/>Alterations in Complex Motor Performance<br/>Extrapyramidal Motor Syndromes<br/><br/>16 Disorders of the Central and Peripheral Nervous Systems and Neuromuscular Junction<br/>Central Nervous System Disorders<br/>Peripheral Nervous System and Neuromuscular Junction Disorders<br/>Tumours of the Central Nervous System<br/><br/>17 Alterations of Neurological Function in Children<br/>Development of the Nervous System in Children<br/>References<br/>Structural Malformations<br/>Alterations in Function: Encephalopathies<br/>Cerebrovascular Disease in Children<br/>Childhood Tumours<br/><br/>Unit 5 The Endocrine System<br/>18 Mechanisms of Hormonal Regulation<br/>Mechanisms of Hormonal Regulation<br/>Structure and Function of the Endocrine Glands<br/>Geriatric Considerations<br/><br/>19 Alterations of Hormonal Regulation<br/>Mechanisms of Hormonal Alterations<br/>Alterations of the Hypothalamic-Pituitary System<br/>Alterations of Thyroid Function<br/>Alterations of Parathyroid Function<br/>Dysfunction of the Endocrine Pancreas: Diabetes Mellitus<br/>Alterations of Adrenal Function<br/><br/>Unit 6 The Hematological System<br/>20 Structure and Function of the Hematological System<br/>Components of the Hematological System<br/>Development of Blood Cells<br/>Mechanisms of Hemostasis<br/>Pediatric Considerations<br/>Geriatric Considerations<br/><br/>21 Alterations of Hematological Function<br/>Alterations of Erythrocyte Function<br/>Myeloproliferative Red Blood Cell Disorders<br/>Alterations of Leukocyte Function<br/>Alterations of Lymphoid Function<br/>Alterations of Splenic Function<br/>Hemorrhagic Disorders and Alterations of Platelets and Coagulation<br/><br/>22 Alterations of Hematological Function in Children<br/>Disorders of Erythrocytes<br/>Disorders of Coagulation and Platelets<br/>Neoplastic Disorders<br/><br/>Unit 7 The Cardiovascular and Lymphatic Systems<br/>23 Structure and Function of the Cardiovascular and Lymphatic Systems<br/>The Circulatory System<br/>The Heart<br/>The Systemic Circulation<br/>The Lymphatic System<br/><br/>24 Alterations of Cardiovascular Function<br/>Diseases of the Veins<br/>Diseases of the Arteries<br/>Disorders of the Heart Wall<br/>Manifestations of Heart Disease<br/>Shock<br/><br/>25 Alterations of Cardiovascular Function in Children<br/>Congenital Heart Disease<br/>Acquired Cardiovascular Disorders<br/><br/>Unit 8 The Pulmonary System<br/>26 Structure and Function of the Pulmonary System<br/>Structures of the Pulmonary System<br/>Function of the Pulmonary System<br/>Geriatric Considerations<br/><br/>27 Alterations of Pulmonary Function<br/>Clinical Manifestations of Pulmonary Alterations<br/>Disorders of the Chest Wall and Pleura<br/>Pulmonary Disorders<br/><br/>28 Alterations of Pulmonary Function in Children<br/>Disorders of the Upper Airways<br/>Disorders of the Lower Airways<br/>Sudden Unexpected Infant Death<br/><br/>Unit 9 The Renal and Urological Systems<br/>29 Structure and Function of the Renal and Urological Systems<br/>Structures of the Renal System<br/>Renal Blood Flow<br/>Kidney Function<br/>Tests of Renal Function<br/>Pediatric Considerations<br/>Geriatric Considerations<br/><br/>30 Alterations of Renal and Urinary Tract Function<br/>Urinary Tract Obstruction<br/>Urinary Tract Infection<br/>Glomerular Disorders<br/>Acute Kidney Injury<br/>Chronic Kidney Disease<br/><br/>31 Alterations of Renal and Urinary Tract Function in Children<br/>Structural Abnormalities<br/>Glomerular Disorders<br/>Nephroblastoma<br/>Bladder Disorders<br/>Urinary Incontinence<br/><br/>Unit 10 The Reproductive Systems<br/>32 Structure and Function of the Reproductive Systems<br/>Development of the Reproductive Systems<br/>The Female Reproductive System<br/>Structure and Function of the Breast<br/>The Male Reproductive System<br/>Aging and Reproductive Function<br/><br/>33 Alterations of the Female Reproductive System<br/>Abnormalities of the Female Reproductive Tract<br/>Alterations of Sexual Maturation<br/>Disorders of the Female Reproductive System<br/>Disorders of the Female Breast<br/><br/>34 Alterations of the Male Reproductive System<br/>Alterations of Sexual Maturation<br/>Disorders of the Male Reproductive System<br/>References<br/>Disorders of the Male Breast<br/>Sexually Transmitted Infections<br/><br/>Unit 11 The Digestive System<br/>35 Structure and Function of the Digestive System<br/>The Gastro-Intestinal Tract<br/>Accessory Organs of Digestion<br/>Geriatric Considerations<br/><br/>36 Alterations of Digestive Function<br/>Disorders of the Gastro-Intestinal Tract<br/>Disorders of the Accessory Organs of Digestion<br/>Cancer of the Digestive System<br/><br/>37 Alterations of Digestive Function in Children<br/>Disorders of the Gastro-Intestinal Tract<br/>Disorders of the Liver<br/>Gastro-Intestinal Malignancies in Children<br/><br/>Unit 12 The Musculo-skeletal and Integumentary Systems<br/>38 Structure and Function of the Musculo-skeletal System<br/>Structure and Function of Bones<br/>Structure and Function of Joints<br/>Structure and Function of Skeletal Muscles<br/>Aging and the Musculo-skeletal System<br/><br/>39 Alterations of Musculo-skeletal Function<br/>Musculo-skeletal Injuries<br/>Disorders of Bones<br/>Disorders of Joints<br/>Disorders of Skeletal Muscle<br/>Musculo-skeletal Tumours<br/><br/>40 Alterations of Musculo-skeletal Function in Children<br/>Congenital Defects<br/>Bone Infection<br/>Juvenile Idiopathic Arthritis<br/>Osteochondroses<br/>Scoliosis<br/>Muscular Dystrophy<br/>Musculo-skeletal Tumours<br/>Nonaccidental Trauma<br/><br/>41 Structure, Function, and Disorders of the Integument<br/>Structure and Function of the Skin<br/>Disorders of the Skin<br/>Disorders of the Hair<br/>Disorders of the Nail<br/>Geriatric Considerations<br/><br/>42 Alterations of the Integument in Children<br/>Acne Vulgaris<br/>Dermatitis<br/>Infections of the Skin<br/>Insect Bites and Parasites<br/>Cutaneous Hemangiomas and Vascular Malformations<br/>Other Skin Disorders<br/><br/>Index<br/> 
<br/><br/><label>ISBN: </label>9781771721172, 9780323354097 
<br/><br/><label>LCCN: </label>2007935686 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Physiology, Pathological.<br/>Nurses.
<br/><br/><label>LC Class. No.: </label>QT 104 T22u 2017