Molecular diagnostics /
edited by George P. Patrinos, Wilhelm Ansorge.
- Amsterdam ; Boston : Elsevier Academic Press, c2005.
- xvi, 461 p. : ill. ; 29 cm.
Includes bibliographical references and index.
Contents
Section 1. Molecular diagnostic technology Chapter 1.Molecular Diagnostics: Past, Present and Future Chapter 2.Allele-Specific Mutation Detection By PCR-ARMS And PCR-ASO Chapter 3.Competitive Oligopriming Chapter 4.Oligonucleotide Ligation Assays for the Diagnosis of Inherited Diseases Chapter 5.Enzymatic and Chemical Cleavage Methods to Identify Genetic Variation Chapter 6.Mutation Detection by Single Strand Conformation Polymorphism and Heteroduplex Analysis Chapter 7.Capillary Electrophoresis Chapter 8.Temperature and Denaturing Gradient Gel Electrophoresis Chapter 9.Two-Dimensional Gene Scanning Chapter 10.Real-Time Polymerase Chain Reaction Chapter 11.Pyrosequencing Chapter 12.Molecular Cytogenetics In Molecular Diagnostics Chapter 13.Detection of Genomic Duplications and Deletions Chapter 14.Analysis of Human Splicing Defects Using Hybrid Minigenes Chapter 15.DNA Microarrays and Genetic Testing Chapter 16.Human Genome Microarray In Biomedical Applications Chapter 17.Use of High Throughput Mass Spectrographic Methods To Identify Disease Processes Chapter 18.The Application of Proteomics To Disease Diagnostics
Section 2: Applications of molecular diagnosis and related issues Chapter 19.Identification of Genetically Modified Organisms Chapter 20.Pharmacogenetics and Pharmacogenomics: Impact on Drug Discovery and Development Chapter 21.Molecular Diagnostic Applications in Forensic Science Chapter 22.Molecular Diagnostics and Comparative Genomics in Clinical Microbiology Chapter 23.Preimplantation Genetic Diagnosis Chapter 24.Genetic Monitoring of Laboratory Animals Chapter 25.The Use of Locus-Specific Databases in Molecular Diagnostics Chapter 26.Safety Analysis in Retroviral Gene Therapy: Identifying virus integration sites in gene-modified cells Chapter 27.Automated DNA Hybridisation and Detection Chapter 28.The Use of Microelectronic-Based Techniques in Molecular Diagnostic Assays Chapter 29.Miniaturization technologies for molecular diagnostics Chapter 30.Human Gene Patents and Genetic Testing Chapter 31.Genetic Counseling and Ethics in Molecular Diagnostics Chapter 32.Genetic Testing and Psychology Chapter 33.Safety in Biomedical and Other Laboratories Chapter 34.Quality Management in the Laboratory