Marks' basic medical biochemistry : a clinical approach /
Basic medical biochemistry
Colleen Smith, Allan Marks, Michael Lieberman ; illustrations by Matthew Chansky
- 2nd edition.
- Philadelphia : Lippincott Williams & Wilkins, c2005.
- xii, 977 p. : ill. ; 28 cm. + 1 CD-ROM (4 3/4 in.)
Includes bibliographical references and index.
Table of content 1. Metabolic fuels and dietary components -- 2. The fed or absorptive state -- 3. Fasting -- 4. Water, acids, bases, and buffers -- 5. Structures of the major compounds of the body -- 6. Amino acids in proteins -- 7. Structure-function relationships in proteins -- 8. Enzymes as catalysts -- 9. Regulation of enzymes -- 10. Relationship between cell biology and biochemistry -- 11. Cell signaling by chemical messengers -- 12. Structure of the nucleic acids -- 13. Synthesis of DNA -- 14. Transcription : synthesis of RNA -- 15. Translation : synthesis of proteins -- 16. Regulation of gene expression -- 17. Use of recombinant DNA techniques in medicine -- 18. The molecular biology of cancer -- 19. Cellular bioenergetics : ATP and O[subscript 2] -- 20. Tricarboxylic acid cycle -- 21. Oxidative phosphorylation and mitochondrial function -- 22. Generation of ATP from glucose : glycolysis -- 23. Oxidation of fatty acids and ketone bodies -- 24. Oxygen toxicity and free radical injury -- 25. Metabolism of ethanol -- 26. Basic concepts in the regulation of fuel metabolism by insulin, glucagon, and other hormones -- 27. Digestion, absorption, and transport of carbohydrates -- 28. Formation and degradation of glycogen -- 29. Pathways of sugar metabolism : pentose phosphate pathway, fructose, and galactose metabolism -- 30. Synthesis of glycosides, lactose, glycoproteins, and glycolipids -- 31. Gluconeogenesis and maintenance of blood glucose levels -- 32. Digestion and transport of dietary lipids -- 33. Synthesis of fatty acids, triacylglycerols, and the major membrane lipids -- 34. Cholesterol absorption, synthesis, metabolism, and fate -- 35. Metabolism of the eicosanoids -- 36. Integration of carbohydrate and lipid metabolism -- 37. Protein digestion and amino acid absorption -- 38. Fate of amino acid nitrogen : urea cycle -- 39. Synthesis and degradation of amino acids -- 40. Tetrahydrofolate, vitamin B12, and S-adenosylmethionine -- 41. Purine and pyrimidine metabolism -- 42. Intertissue relationships in the metabolism of amino acids -- 43. Actions of hormones that regulate fuel metabolism -- 44. The biochemistry of the erythrocyte and other blood cells -- 45. Blood plasma proteins, coagulation, and fibrinolysis -- 46. Liver metabolism -- 47. Metabolism of muscle at rest and during exercise 48. Metabolism of the nervous system 49. The extracelluar matrix and connective tissue.