TY - BOOK AU - Singh,Gurmit AU - Orr,F.William TI - Bone metastasis and molecular mechanisms: pathophysiology T2 - Cancer metastasis-biology and treatment SN - 140201984X AV - QZ 203 B712 2004 PY - 2004/// CY - Dordrecht, Boston PB - Kluwer Academic KW - Bone metastasis KW - Cancer KW - Pathophysiology KW - Molecular aspects N1 - Includes bibliographical references and index; Contents Chapter 1............................. .........................1 Models of Breast Cancer Metastasis to Bone: Characterization of a Clinically Relevant Model Belinda S. Parker, Bederich L. Eckhardt and Robin L. Anderson Chapter 2 ..... ....................... ........................19 Quantitation of Bone Metastasis in Experimental Systems Julie A. Sharp and Erik W. Thompson Chapter 3 ................................................31 Comparative Morphometric Study on Bone Remodeling in Human Specimens and in Experimental Models of Metastatic Bone Disease Snezana Vukmirovic-Popovic, Eric Seidlitz, F. William Orr and Gurmit Singh Chapter 4 .................................................... 49 Clinical Modalities for the Diagnosis, Characterization and Detection of Bone Metastases Michael H. Weber, Jonathan C. Sharp, Thomas H. Hassard, Martin Reed, James A. Thliveris and F. William Orr Chapter 5 ..................................................................71 Metastasis in the Bone Marrow Microenviroment Paolo Bianco, Mara Riminucci and Pamela Gehron Robey Chapter 6 ...... ........... ..................................87 The Role of Tumor-Associated Macrophages in Metastasis- Associated Osteolysis Nicholas. A. Athanasou Chapter 7 .................. ...............................109 The Malignant Hierarchy in Multiple Myeloma: Relationships between Malignant Cells and Bone Disease Linda M. Pilarski, Tony Reiman, Patrick M. Pilarski, F. William Orr and Andrew R. Belch Chapter 8 ................... .............................139 Angiogenesis and Lymphangiogenesis in Metastatic Bone Disease: A Matter of Networking Gabri Van Der Pluijm, and Jereon Buijs Chapter 9 .................... ... ... ..........................163 Prostate Cancer: Models for Developing Novel Therapeutic Approaches Shafaat A. Rabbani, Nicholas Shukeir and Andrew P. Mazar Chapter 10 . ...................... ...................187 Potential Therapeutic Targets for Bone Metastasis Sadmeet Singh and Gurmit Singh Chapter 11 .... ..... ......................................... 211 OPG, RANK and RANKL in Bone Metastasis and Cancer- Associated Osteolysis Paul J. Kostnuik Chapter 12...................... ................................ 241 Role of Matrix Metalloproteinases in Bone Metastasis from Human Breast and Prostate Cancer Wilhelmina C.M Duivendoorden and Gurmit Singh Chapter 13 ... .................... ..................... ..277 The Role of Bisphosphonates in Bone Metastasis Mary Mackenzie and Pierre Major UR - http://www.loc.gov/catdir/toc/fy045/2004300039.html UR - http://www.loc.gov/catdir/enhancements/fy0821/2004300039-d.html ER -