Bone metastasis and molecular mechanisms : pathophysiology /
edited by Gurmit Singh and William Orr.
- Dordrecht ; Boston : Kluwer Academic, 2004.
- xvi, 308 p. : ill. ; 25 cm.
- Cancer metastasis-biology and treatment ; v. 6 .
- Cancer metastasis ; v. 6 .
Includes bibliographical references and index.
Contents
Chapter 1............................. .........................1 Models of Breast Cancer Metastasis to Bone: Characterization of a Clinically Relevant Model Belinda S. Parker, Bederich L. Eckhardt and Robin L. Anderson
Chapter 2 ..... ....................... ........................19 Quantitation of Bone Metastasis in Experimental Systems Julie A. Sharp and Erik W. Thompson
Chapter 3 ................................................31 Comparative Morphometric Study on Bone Remodeling in Human Specimens and in Experimental Models of Metastatic Bone Disease Snezana Vukmirovic-Popovic, Eric Seidlitz, F. William Orr and Gurmit Singh
Chapter 4 .................................................... 49 Clinical Modalities for the Diagnosis, Characterization and Detection of Bone Metastases Michael H. Weber, Jonathan C. Sharp, Thomas H. Hassard, Martin Reed, James A. Thliveris and F. William Orr
Chapter 5 ..................................................................71 Metastasis in the Bone Marrow Microenviroment Paolo Bianco, Mara Riminucci and Pamela Gehron Robey
Chapter 6 ...... ........... ..................................87 The Role of Tumor-Associated Macrophages in Metastasis- Associated Osteolysis Nicholas. A. Athanasou
Chapter 7 .................. ...............................109 The Malignant Hierarchy in Multiple Myeloma: Relationships between Malignant Cells and Bone Disease Linda M. Pilarski, Tony Reiman, Patrick M. Pilarski, F. William Orr and Andrew R. Belch
Chapter 8 ................... .............................139 Angiogenesis and Lymphangiogenesis in Metastatic Bone Disease: A Matter of Networking Gabri Van Der Pluijm, and Jereon Buijs
Chapter 9 .................... ... ... ..........................163 Prostate Cancer: Models for Developing Novel Therapeutic Approaches Shafaat A. Rabbani, Nicholas Shukeir and Andrew P. Mazar
Chapter 10 . ...................... ...................187 Potential Therapeutic Targets for Bone Metastasis Sadmeet Singh and Gurmit Singh
Chapter 11 .... ..... ......................................... 211 OPG, RANK and RANKL in Bone Metastasis and Cancer- Associated Osteolysis Paul J. Kostnuik
Chapter 12...................... ................................ 241 Role of Matrix Metalloproteinases in Bone Metastasis from Human Breast and Prostate Cancer Wilhelmina C.M Duivendoorden and Gurmit Singh
Chapter 13 ... .................... ..................... ..277 The Role of Bisphosphonates in Bone Metastasis Mary Mackenzie and Pierre Major
140201984X
Bone metastasis. Cancer--Pathophysiology. Cancer--Molecular aspects.