TY  - BOOK
AU  - Li,Wen-Hsiung
AU  - Graur,Dan
TI  - Fundamentals of molecular evolution
SN  - 0878934529 
U1  - 575.1 20
PY  - 1991///
CY  - Sunderland, Mass.
PB  - Sinauer Associates
KW  - Molecular evolution
N1  - Contents;

Introduction: What is molecular evolution?
1. Gene structure and mutation 
DNA sequences 
Gene structure 
Genetic codes 
Mutation 

2. Dynamics of genes in populations 
Changes in allele frequencies 
Natural selection 
Random genetic drift 
Effective population size 
etc.

3. Evolutionary change in nucleotide sequences 
Nucleotide substitution in a DNA sequence 
Number of nucleotide substitutions between two DNA sequences 
Alignment of nucleotide and amino acid sequences 
Indirect estimation of the number of nucleotide substitutions 

4. Rates and patterns of nucleotide substitution 
Rates of nucleotide substitution 
Causes of variation in substitution rates 
A case of positive selection: Lysozyme in cows and langurs 
Molecular clocks 
etc.

5. Molecular phylogeny 
Impact of molecular data on phylogenetic studies 
Phylogenetic trees 
Methods of tree reconstruction 
Phenetics versus cladistics 
Estimation of branch lengths 
etc.

6. Evolution by gene duplication and exon shuffling 
Types of DNA duplication 
Domains and exons
Domain duplication and gene elongation 
Formation of gene families and the acquisition of new functions 
etc

7. Evolution by transposition 
Transposition and retroposition 
Transposable elements 
Retrosequences 
Effects of transposition on the host genome 
Hybrid dysgenesis 
Transposition and speciation 
etc.

8. Genome organization and evolution 
C values 
Evolution of genome size in bacteria 
Genome size of eukaryotes and the C-value paradox 
The repetitive structure of the eukaryotic genome 
Mechanisms for increasing genome size 
etc.

; Includes bibliographical references and index
ER  -