TY - BOOK AU - Knight,Robin TI - Transfusion and transplantation science T2 - Fundamentals of biomedical science SN - 9780199533282 (alk. paper) U1 - 615.39 23 PY - 2013/// CY - Oxford PB - Oxford University Press KW - Transplantation of organs, tissues, etc KW - Blood Component Transfusion KW - Transplantation N1 - Contents; 1. Introduction to basic immunology and techniques 1.1 Basic immunology and techniques 1.2 Antibody structure 1.3 Antibody structure 1.4 Antigen-antibody reactions etc. 2. Human erythrocyte antigens or blood groups 2.1 The ABO, H and Lewis blood groups and systems 2.2 The Lewis blood group system and secretor 2.3 The MNS blood group system 2.4 The Rh, RHAG, and LW blood group systems etc. 3. Donors and donation: Collection and processing 3.1 Blood donation 3.2 Donor/donation linking 3.3 Component preparation 3.4 Pathogen reduction etc. 4. Blood donation testing 4.1 Mandatory testing 4.2 Additional testing 4.3 Microbiology serology testing 4.4 Microbiology positive screen confirmatory testing etc. 5. Clinical use of blood components 5.1 Structure and function of blood 5.2 Normal physiological response to anaemia and/or bleeding 5.3 Blood components available and their appropriate use 5.4 Blood products etc 6. Compatibility testing and adverse effects 6.1 Compatibility testing 6.2 Selection of plasma products 6.3 Selection of cellular components 6.4 Visual inspection and labelling of the units etc. 7. Immune red cell destruction 7.1 What is immune red cell destruction? 7.2 Clinical significance of red cell antibodies 7.3 Haemolytic transfusion reactions 7.4 Autoimmune haemolytic anaemias etc. 8. Human leucocyte antigens and their clinical significance 8.1 A brief history of transplantation 8.2 Human leucocyte antigens 8.3 The detection and definition of human leucocyte antigens, alleles and antibodies etc. 9. Human platelet antigens and human neutrophil antigens and their clinical significance 9.1 Overview of platelet and granulocyte antigens 9.2 Human platelet antigens 9.3 Human neutrophil antigens etc. 10. Haemopoietic stem cell banking 10.1 Stem cells 10.2 Major histocompatibility complex and human lymphocyte antigens 10.3 Sources of haemopoietic stem cells etc. 11. Tissue banking 11.1 Types of graft 11.2 Which tissues are banked and how ae they used? 11.3 How are donors selected, screened and consented? etc. 12. Quality issues 12.1 Evolution of quality 12.2 Quality management systems 12.3 Blood safety and quality regulations etc. ; Includes bibliographical references and index ER -