TY  - BOOK
AU  - Shargel,Leon
AU  - Yu,Andrew B.C.
TI  - Applied biopharmaceutics & pharmacokinetics
SN  - 9780071830935
U1  - 615.7 23
PY  - 2016///]
CY  - New York
PB  - McGraw-Hill Education
KW  - Biopharmaceutics
KW  - Pharmacokinetics
KW  - Drug Administration Routes
KW  - Models, Chemical
N1  - Contents;

Chapter 1: Introduction to Biopharmaceutics and Pharmacokinetics
Chapter 2: Mathematical Fundamentals in Pharmacokinetics
Chapter 3: Biostatistics
Chapter 4: One-Compartment Open Model: Intravenous Bolus Administration
Chapter 5: Multicompartment Models: Intravenous Bolus Administration

Chapter 6: Intravenous Infusion
Chapter 7: Drug Elimination, Clearance, and Renal Clearance
Chapter 8: Pharmacokinetics of Oral Absorption
Chapter 9: Multiple-Dosage Regimens
Chapter 10: Nonlinear Pharmacokinetics

Chapter 11: Physiologic Drug Distribution and Protein Binding
Chapter 12: Drug Elimination and Hepatic Clearance
Chapter 13: Pharmacogenetics and Drug Metabolism
Chapter 14: Physiologic Factors Related to Drug Absorption

Chapter 15: Biopharmaceutic Considerations in Drug Product Design and In Vitro Drug Product Performance
Chapter 16: Drug Product Performance, In Vivo: Bioavailability and Bioequivalence
Chapter 17: Biopharmaceutical Aspects of the Active Pharmaceutical Ingredient and Pharmaceutical Equivalence
Chapter 18: Impact of Biopharmaceutics on Drug Product Quality and Clinical Efficacy
Chapter 19: Modified-Release Drug Products and Drug Devices

Chapter 20: Targeted Drug Delivery Systems and Biotechnological Products
Chapter 21: Relationship Between Pharmacokinetics and Pharmacodynamics
Chapter 22: Application of Pharmacokinetics to Clinical Situations
Chapter 23: Application of Pharmaco­kinetics to Specific Populations: Geriatric, Obese, and Pediatric Patients
Chapter 24: Dose Adjustment in Renal and Hepatic Disease
Chapter 25: Empirical Models, Mechanistic Models, Statistical Moments, and Noncompartmental Analysis
; Includes bibliographical references and index
ER  -