TY  - BOOK
AU  - Bilezikian,John P.
AU  - Raisz,Lawrence G.
AU  - Rodan,Gideon A.
TI  - Principles of bone biology
SN  - 9780120986538
U1  - 573.1556 22
PY  - 2002///
CY  - San Diego
PB  - Academic Press
KW  - Bones
KW  - Physiology
KW  - Molecular aspects
N1  - Contents;

Volume one 
1. Basic principles 
A. Cell biology
Structure and development of the skeleton 
Biomechanics 
Embryonic development of bone and the molecular regulation and endochondral bone formation 
Mesenchymal stem cells and osteoblast differentiation 
Transcriptional control of osteoblast differentiation and function 
etc. 

B. Biochemistry 
Type I collagen: Structure, synthesis and regulation 
Collagen cross-linking and metabolism 
Bone matrix proteoglycans 
Osteopontin 
Bone proteinases 
Integrins and other cell surface attachment molecules of bone cells 
etc.

C. Bone remodeling and mineral homeostasis 
Histomorphometric analysis of bone remodeling 
Phosphorus homeostasis and related disorders 
Magnesium homeostasis 
Metals in bone: Aluminum, boron, cadmium, chromium, lead, silicon and strontium 
etc.

D. The hormones of bone 
Receptors for parathyroid hormone(PTH) and PTH-related peptide 
Parathyroid hormone: Molecular biology 
Parathyroid hormone: Receptor interactions 
etc.

Volume two 
Vascular endothelial growth factors 
Transforming growth factor 
Bone morphogenetic proteins 
Bone morphogenetic protein receptors and actions 
etc.

2. Molecular mechanisms of metabolic bone diseases 
Molecular basis of PTH overexpression 
Familial benign hypocalciuric hypercalcemia and neonatal primary hyperparathyroidism 
Multiple endocrine neoplasia type I
etc.

3. Pharmacological mechanisms of therapeutic 
Parathyroid hormone Calcium 
Calcium receptors as novel drug targets 
Bisphosphonates mechanisms of action 
Fluoride in osteoporosis 
etc.

4. Methods in bone research 
Application of transgenic mice to problems of skeletal biology 
Use of cultured osteoblastic cells to identify and characterize transcriptional regulatory complexes 
Current methodologic issues in cell tissue culture 
Biochemical markers of bone metabolism 
etc.

; Includes bibliographical references and index
UR  - http://www.loc.gov/catdir/description/els031/2001090660.html
UR  - http://www.loc.gov/catdir/toc/els031/2001090660.html
ER  -