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The liver : biology and pathobiology / editor-in-chief, Irwin M. Arias ; associate editors, James L. Boyer ... [et al.].

Contributor(s): Publication details: Philadelphia : Lippincott Williams & Wilkins, 2001Edition: 4th editionDescription: xvi, 1064 p., [16] p. of plates : ill. (some col.), map; 29 cmISBN:
  • 0781723906
  • 9780781723909
Subject(s): DDC classification:
  • 612.35 21 LIV
NLM classification:
  • WI 702
Online resources:
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Item type Current library Call number Copy number Status Date due Barcode
Book Open Access Book Open Access Health Sciences Library 612.35 LIV 1 (Browse shelf(Opens below)) 1 Available MBAL22010728

Contents

INTRODUCTION
Organizational Principles
Embryonic Development of the Liver

THE CELLS
Gap and Tight Junctions in Liver :Composition, Regulation, and Function
Motor Molecules
Gene Regulation and In Vivo Function of Liver Transcription Factors
The Hepatocyte Plasma Membrane:Organization, Differentiation, Biogenesis,and TurnoverHepatocyte Basolateral Membrane Organic Anion Transporters
The Hepatocyte Surface:Dynamic Polarity
The Endoplasmic Reticulum and Golgi Complex in Secretory Membrane Transport
Molecular Mechanisms of Hepatocellular Vesicle Formation
Receptor-Mediated Endocytosis
Peroxisomal Assembly, Biology, and Disease Relationship

SECTION A: HEPATOCYTE:METABOLISM
Integrated Cell Function:Apoptosis
Fundamentals of Cellular Osmoregulation
Roles of Intracellular Proteolysis in Hepatocyte Cell-Cycle,Aging, and Programmed Cell Death
Regulation of Hepatic Cholesterol Homeostasis
Leptin and the Liver
Hypoxic, Ischemic, and Reperfusion Injury to LiverProtective Mechanisms Against Reactive oxygen Species
Disorders of Bilirubin Metabolism
The Porphyrias
Copper Metabolism and the LiverThe Liver and Iron

SECTION B:BILE SECRETION
The Biology of the Bile Canaliculus
Conjugate Export Pumps of the Multidrug Resistance Protein (MRP) Family in Liver
Genetic Defects of Canalicular Transport
Hormonal Regulation of Bile Secretion
Nucleotide Transport and Regulation of Bile Formation
The Pathobiology of Biliary Epithelia

SECTION C:SINUSOIDAL CELLS
Endothelial and Pit Cells
Hepatic Stellate Cells:Morphology, Function, and Regulation

SECTION D:EXTRACELLULAR MATRIX
The Extracellular Matrix of the LiverIntegrins

INTERRELATED CELL FUNCTIONS
Role of Inositol Trisphosphate and Diacylglycerol in the Regulation of Liver Function
Synthesis of an Signaling Through D-3 Phosphoinositides
Insulin and Other Growth Factors
Cyclic AMP Signaling in the Liver:Coupling Transcription to Psysiology and Proliferation
CA2+ Signaling in the Liver
Nitric Oxide in the Liver
Interleukin-6 Signaling During the Acute-Phase Response of the LiverInnate Immune Sensing and the Toll-Like ReceptorsLiver Regeneration Hepatocyte Growth Factor:Its Role in Hepatic Growth and Pathobiology

THE ORGANRELATION TO OTHER ORGANS
Hepatic Encephalopathy
Alterations of the Kidney in Liver Disease

PATHOBIOLOGIC ANLYSISMolecular Pathophysiology of Membrane Transport Function in Cholestasis
The Biology of Portal Hypertension
1-Antitrypsin Deficiency
Pathophysiology of Liver Fibrosis
Alcoholic and Nonalcoholic
SteatohepatitisSchistosomiasis:A Model of Immunologically Mediated Liver Disease
Immune Mechanisms of Viral Clearance, and Disease Pathogenesis During Viral Hepatitis
Epidemiology, Natural History, and Prevention of Viral Hepatitis
Molecular Bases of Hepatitis B and Hepatitis C Related Chronic
Liver DiseaseMolecular Biology of Hepatitis Viruses
Liver Transplantation:Factors Affecting the Balance Between Tolerance and Rejection in Experimental Models
Viral Hepatitis:Antiviral Therapy

HORIZONS
Tissue Engineering of the Liver
A Genomic View of Hepatology

Includes bibliographical references and index.

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