Gynecological cancers Section 1 Molecular Biology of Gynecologic cancers Endometrial Cancer Ovarian cancer Section 2 Cancer of cervix, vagina, and vulva Carcinoma of the cervix Carcinoma of the cervical Carcinoma of the vagina Section 3 cancers of the uterine Body Endometrial cancer Uterine sarcomas Section 4 Gestational Trophoblastic Diseases Epidemiology Pathology and Biology Section 5 Ovarian cancer, Fallopian Tube carcinoma and peritoneal carcinoma Ovarian cancer Borderline tumor 37 Cancer of the breast Section 1 Molecular Biology of the Breast cancer Genetics Steroid and growth factor pathways of cellular regulation Section 2 Malignant Tumor s of the breast Risk factors for breast cancer Management of the high risk-patient Breast cancer prevention Section 3 Rehabilitation after treatment for cancer of the breast Delayed versus immediate reconstruction Prosthetic reconstruction 38 Cancer of the Endocrine system Section 1 Molecular biology of endocrine tumors Multiple endocrine neoplasia syndrome Molecular pathogenesis of sporadic thyroid neoplasms Section 2 Thyroid tumors Thyroid nodules Well-differentiated thyroid carcinoma Section 3 Parathyroid tumors Primary Hyper parathyroid Section 4 Adrenal Tumors Pathology of the adrenal cortex Adrenal cortical adenoma Section 5 Pancreatic endocrine tumors Pathogenesis, pathologic features, and tumor biology. Clinical presentation and diagnosis Section 6 Carcinoids tumors and the carcinoid syndrome Pathology and tumor histology Molecular pathogenesis Section 7 Multiple endocrine neoplasias Multiple endocrine neoplasia type 1 Familial medullary thyroid carcinoma and multiple endocrine 39 Sarcomas of the soft tissue and bone Section 1 Soft tissue sarcoma Incidence Etiology and genetics Section 2 Sarcomas of bone Classification and types of bone tumors Radiographic evaluation and diagnosis 40 Benign and Malignant mesothelioma Section 1 Molecular biology of mesothelioma Mechanism of asbestos- induced oncogenesis Cytogenetic assessment of malignant mesotheliomas Section 2 Management of mesothelioma Epidemiology Biology of mesothelioma 41 Cancer of the skin Section 1 Molecular biology of skin cancer Skin carcinogens Genetic events Section 2 Management of skin cancer Diagnosis General approach to management of skin cancer 42 Melanoma Section 1 Molecular biology of cutaneous melanoma Etiology of melanoma Genetics of melanoma Section 2 Cutaneous melanoma Epidemiology Risk factors, prevention, and screening Section 3 Intraocular melanoma Epidemiology Etiology and histogenesis of ocular melanomas 43 Neoplasms of the central nervous system Section 1 molecular biology of central nervous system neoplasms Diffuse, fibrillary astrocytoma Other gliomas Section 2 Neoplasms of the central nervous system Incidence and classification Genetic, molecular, environmental, viral, and other factors 44 Cancers of childhood Section 1 molecular biology of child cancers Tumor suppressor Renoblastoma: the paradigm Section 2 solid tumors of childhood Epidemiology Management of childhood cancer 45 Lymphomas Section 1 Molecular biology of of lymphomas Histogenetic pathways of lymphoma General mechanisms of genetic lesions in lymphoma Section 2 leukemia and lymphomas of childhood Leukemia Non-Hodgkin’s lymphoma
46 Leukemia’s Section 1 molecular biology of leukemia’s Gene fusions in leukemia’s Gene activation in leukemia Section 2 acute leukemia’s Epidemiology and etiology Biology of acute leukemia Section 3 chronic leukemia Epidemiology and etiology Biology of acute leukemia Section 4 plasma cell neoplasms History Epidemiology Etiology Section 5 myelodysplastic syndromes Incidence Etiology Classification and risk groups 47 Paraneoplastic syndromes Endocrinology manifestations of cancer Hematologic manifestations of cancer 48 Cancer of unknown primary site Poorly differentiated neoplasms of unknown primary site Adenocarcinoma of unknown primary site 49 Peritoneal carcinomatosis 50 Immunosuppression- related malignancies Section 1 AIDS- related malignancies Section 2 transplantation – related malignancies 51 Oncologic emergencies Section 1 superior vena cava syndrome Section 2 spinal cord compression Section 3 Metabolic emergencies Section 4 urologic emergencies 52 Treatment of metastatic cancer Section 1 metastatic brain cancer Section 2 metastatic cancer of the lung Section 3 metastatic cancer to the liver Section 4 metastatic cancer to the bone Section 5 malignant pleural and pericardial effusions Section 6 malignant ascites 53 Hematopoietic therapy Section 1 transfusion therapy Section 2 autologous stem cell transplantation Section 3 allogeneic stem cell transplantation Section 4 hematopoietic growth factors 54 Infections in the cancer patient 55 Adverse effects of treatment Section 1 nausea and vomiting Section 2 oral complications Section 3 pulmonary toxicity Section 4 cardiac toxicity Section 5 hair loss Section 6 gonadal dysfunction Section 7 second cancers Section 8 miscellaneous toxicities 56 Supportive care and quality of life Section 1 management of cancer Section 2 nutritional support Section 3 sexual problems Section 4 genetic counseling Section 5 psychological issues Section 6 community resources Section 7 specialized care of the terminally ill 57 Rehabilitation of the cancer patient 58 Advanced practice nurses and physician assistants in oncology care 59 Ethical issues in oncology and clinical trials 60 Information systems in oncology 61 Complementary, alternative, and unproven methods of cancer treatment
PART 4 NEWER APPROACHES IN CANCER TREATMENT 62 Genetic therapy Section 1 gene therapy Section 2 molecular therapy 63 Cancer vaccines Section 1 preventive cancer vaccines Section 2 therapeutic cancer vaccine 64 Image – guided surgery 65 Proton beam radiation therapy
Includes index.
6 Leukemia’s Section 1 molecular biology of leukemia’s Gene fusions in leukemia’s Gene activation in leukemia Section 2 acute leukemia’s Epidemiology and etiology Biology of acute leukemia Section 3 chronic leukemia Epidemiology and etiology Biology of acute leukemia Section 4 plasma cell neoplasms History Epidemiology Etiology Section 5 myelodysplastic syndromes Incidence Etiology Classification and risk groups 47 Paraneoplastic syndromes Endocrinology manifestations of cancer Hematologic manifestations of cancer 48 Cancer of unknown primary site Poorly differentiated neoplasms of unknown primary site Adenocarcinoma of unknown primary site 49 Peritoneal carcinomatosis 50 Immunosuppression- related malignancies Section 1 AIDS- related malignancies Section 2 transplantation – related malignancies 51 Oncologic emergencies Section 1 superior vena cava syndrome Section 2 spinal cord compression Section 3 Metabolic emergencies Section 4 urologic emergencies 52 Treatment of metastatic cancer Section 1 metastatic brain cancer Section 2 metastatic cancer of the lung Section 3 metastatic cancer to the liver Section 4 metastatic cancer to the bone Section 5 malignant pleural and pericardial effusions Section 6 malignant ascites 53 Hematopoietic therapy Section 1 transfusion therapy Section 2 autologous stem cell transplantation Section 3 allogeneic stem cell transplantation Section 4 hematopoietic growth factors 54 Infections in the cancer patient 55 Adverse effects of treatment Section 1 nausea and vomiting Section 2 oral complications Section 3 pulmonary toxicity Section 4 cardiac toxicity Section 5 hair loss Section 6 gonadal dysfunction Section 7 second cancers Section 8 miscellaneous toxicities 56 Supportive care and quality of life Section 1 management of cancer Section 2 nutritional support Section 3 sexual problems Section 4 genetic counseling Section 5 psychological issues Section 6 community resources Section 7 specialized care of the terminally ill 57 Rehabilitation of the cancer patient 58 Advanced practice nurses and physician assistants in oncology care 59 Ethical issues in oncology and clinical trials 60 Information systems in oncology 61 Complementary, alternative, and unproven methods of cancer treatment
PART 4 NEWER APPROACHES IN CANCER TREATMENT 62 Genetic therapy Section 1 gene therapy Section 2 molecular therapy 63 Cancer vaccines Section 1 preventive cancer vaccines Section 2 therapeutic cancer vaccine 64 Image – guided surgery 65 Proton beam radiation therapy
"Cancer: Principles and Practice of Oncology presents the practicing oncologist with the practical as well as cutting-edge information needed to ensure the best possible care for each individual patient. To ensure a balanced multidisciplinary approach, a surgeon, a medical oncologist, and a radiation oncologist author each of the major treatment chapters. Each of the major treatment sections is preceded by an updated, brief chapter describing the molecular biology of that cancer and the prospects this new information holds for the improved management of cancer patients"--